Combined pegylated interferon (PEG-IFN)+ribavirin (RBV) therapy has been used as a primary treatment for chronic hepatitis C. However, IFN-induced autoimmune disease, including type 1 diabetes mellitus, has been highlighted as one of the problems with this therapy. Here we report the case of a patient who developed type 1 diabetes mellitus during combined PEG-IFN+RBV therapy for hepatitis C but...

Autoimmune reactions to vaccinations may rarely be induced in predisposed individuals by molecular mimicry or bystander activation mechanisms. Autoimmune reactions reliably considered vaccine-associated, include Guillain-Barré syndrome after 1976 swine influenza vaccine, immune thrombocytopenic purpura after measles/mumps/rubella vaccine, and myopericarditis after smallpox vaccination, whereas ...

OBJECTIVE Familial clustering of juvenile autoimmune liver disease (AILD), including autoimmune hepatitis and autoimmune sclerosing cholangitis (ASC), is rare, despite a high prevalence of autoimmune disorders in AILD families. METHODS To investigate this discrepancy, we measured autoantibodies diagnostic for AILD, anti-nuclear, anti-smooth muscle, anti-liver kidney microsomal type 1, anti-li...

Autoimmune liver disorders in childhood include autoimmune hepatitis and autoimmune sclerosing cholangitis. These inflammatory liver disorders are characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by autoantibodies and increased levels of immunoglobulin G. Autoimmune hepatitis is particularly aggressive in children and progresse...

background: â  advanced hepatic fibrosis and cirrhosis has generally been considered to be irreversible. the aim of this study was to determine whether cirrhosis is reversible.â  â  methods: â  seven patients with autoimmune hepatitis with histologic evidence of cirrhosis were enrolled. after treatment, they had follow-up liver biopsy while in clinical and biochemical remission. biopsy specimen...

hepatitis a infection is usually a self–limited disease during childhood. autoimmune manifestations are rarely reported among patients with ha infection. we describe a previously healthy 6-yr-old male with acute hepatitis a who developed immune thrombocytopenia.

How to cite this article: Yilmaz B, Kiziltas S, Yildiz S, Gümüs B, Çevik H. Simultaneous Immunoglobulin G4-associated Autoimmune Hepatitis and Autoimmune Pancreatitis. Euroasian J Hepato-Gastroenterol 2017;7(1):95-96.

Autoimmune liver diseases may be associated with extrahepatic autoimmune pathology. We report the case of a 52-year old woman who initially presented to the gastroenterology department for extreme fatigue, pale stools, dark urine and pruritus. Laboratory tests showed significant cholestasis and elevation of aminotransferase levels. Immunological tests revealed positive antinuclear (ANA=1:320) a...

The liver is an organ that withstands a lot of insults due to various things such as infection, toxins and even our own immune system. There are injuries the relatively common in medicine viral hepatitis caused by different strains Hepatitis A-E, autoimmune hepatitis, injury drugs acetaminophen. However, syphilis causing not seen often there certain features distinguish syphilitic should be rep...