We present an overview of learning theory including its statistical and computational aspects. We start by giving a probabilistic formulation of learning problems including classification and regression where the learner knows nothing about the probability distribution generating the data. We then consider the principle of empirical risk minimization (ERM) that chooses a function from a given c...

The core objective of this study was to find out the different factors for investors behaviour as a part their investment option in Gujarat state, author has collected total 150 samples study. To identify which are responsible types biases that have been faced by market, applied exploratory factor analysis identification behaviour. sampling techniques is non probabilistic convenient responses c...

materials and methods an oligogearray® (an oligonucleotide-based gene expression array platform) containing 126 wnt signaling pathway-related genes was used to compare gene expressions between primary hcc and adjacent non-tumorous liver tissues from 10 patients with hcc. selected differential genes were identified with real-time rt-pcr and immunohistochemistry (ihc). in particular, the protein ...

Ribosome profiling is a promising technology for exploring gene expression. However, ribosome profiling data are characterized by a substantial number of outliers due to technical and biological factors. Here we introduce a simple computational method, Ribo-seq Unit Step Transformation (RUST) for the characterization of ribosome profiling data. We show that RUST is robust and outperforms conven...

Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the bowel. The etiology remains unknown, but IBD is immune-driven and multiple factors including genetic, environmental, and microbiological components play a role. Recombinase-activating gene-2deficient (Rag2−/−) mice infected with Helicobacter hepaticus (H. hepaticus) have been developed as an animal model to imi...

José R. Mediavilla, Liang Chen, Anne-Catrin Uhlemann, Blake M. Hanson, Marnie Rosenthal, Kathryn Stanak, Brian Koll, Bettina C. Fries, Donna Armellino, Mary Ellen Schilling, Don Weiss, Tara C. Smith, Franklin D. Lowy, and Barry N. Kreiswirth Author affi liations: University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA (J.R. Mediavilla, L. Chen, B.N. Kreiswirth); Columbia Uni...