In 1991, Arnold Starr and colleagues described an 11-year-old child with the paradoxic findings of absent auditory brainstem responses in the presence of normal cochlear microphonics (CMs) and otoacoustic emissions (OAEs). The child demonstrated severely impaired speech understanding despite a mild loss of hearing sensitivity. Further evaluation showed impaired temporal processing as exhibited ...

Autism Spectrum Disorder (ASD) has an intriguing auditory processing profile. Individuals show enhanced pitch discrimination, yet often find seemingly innocuous sounds distressing. This study used two behavioural experiments to examine whether an increased capacity for processing sounds in ASD could underlie both the difficulties and enhanced abilities found in the auditory domain. Autistic and...

The human auditory cortex is the gateway to the most powerful and complex communication systems and yet relatively little is known about its functional organization as compared to the visual system. Several lines of evidence, predominantly from recent studies, indicate that sound recognition and sound localization are processed in two at least partially independent networks. Evidence from human...

Kartagner's syndrome is a rare autosomal recessive disorder characterized by sinusitis, bronchiectasis and situs inversus. Otitis media is seen in 95% of the individuals with this syndrome due to recurrent respiratory infections and dysfunctional cilia in the middle ear. Earlier research reported the presence of structural and functional deficits in the auditory brainstem following long standin...

Few studies have addressed the long-term outcomes of early brain injury, especially after hemorrhagic stroke. This is the first study to report a case of acquired auditory processing disorder in a 10-year-old child who had a severe left hemorrhagic cerebral infarction at 13 months of age, compromising nearly all of the left temporal lobe. This case, therefore, is an excellent and rare opportuni...

BACKGROUND Disturbances in sensory processing have been hypothesized in individuals with posttraumatic stress disorder (PTSD). The authors investigated this possibility by using mismatch negativity (MMN), an event-related potential (ERP) that reflects the operation of a preconscious cortical detector of stimulus change. METHODS Thirteen medication-free women with sexual assault-related PTSD w...

Developmental apraxia of speech is a disorder of phonological and articulatory output processes. However, it has been suggested that perceptual deficits may contribute to the disorder. Identification and discrimination tasks offer a fine-grained assessment of central auditory and phonetic functions. Seventeen children with developmental apraxia (mean age 8:9, years:months) and 16 control childr...