Attention-deficit/hyperactivity disorder (ADHD) is a prevalent psychiatric disorder in children. Although an imbalance of excitatory and inhibitory inputs has been proposed as contributing to this disorder, the mechanisms underlying this highly heterogeneous disease remain largely unknown. Here, we show that N-myc downstream-regulated gene 2 (NDRG2) deficiency is involved in the development of ...

Attention deficit hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder characterized by a definite behavioral pattern that might lead to performance problems in the social, educational, or work environments. In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, the symptoms of ADHD were restricted to those associated with cognitive (attention de...

The initial results of the Multimodal Treatment of Attention Deficit Hyperactivity Disorder (MTA) trial had profound effects on the way that Attention-Deficit Hyperactivity Disorder (ADHD) is managed clinically. Children from the original MTA cohort as well as a control group have been followed longitudinally for well over a decade and are beginning to provide important data regarding the long-...

Serotonin plays an essential role in cognition, locomotor activity, and the regulation of sleep, pain, mood, and aggression. Polymorphisms of the HTR1B gene have been implicated in a variety of psychiatric disorders including attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). The objectives of this study were to: (i) expand our original investigation of the...

objectives: attention-deficit/hyperactivity disorder (adhd) is the most common neurobehavioral disorder of childhood. children with adhd may experience significant functional problems. our objective was to examine the prevalence of adhd and its subtypes in iran. methods: pubmed, isi web of science, psychinfo, iranpsych, iranmedex, irandoc were searched. irandoc, iranmedex and iranpsych are iran...

attention deficit hyperactivity disorder (adhd) and anxiety is the most common childhood psychiatric disorder. based on studies, these disorders are more prevalent in some chronic disease. this study aimed at investigating the prevalence of adhd and anxiety in children with malignancy and anxiety in their parents and comparing the results with those of the control group. one hundred, 3-15-year-...

Although comorbidity between attention-deficit/hyperactivity disorder (ADHD) and eating disorders (ED) is relevant for clinical treatment, it is seldom investigated. Methods: 86 DSM-IV attention deficity hyperactivity disorder patients out of 107 self-referred adults in a specialized center for attention deficity hyperactivity disorder were interviewed using SCID-R to evaluate the lifetime prev...

children with attention-deficit/hyperactivity disorder (adhd) react explosively and inappropriately to emotional stimuli. it could be hypothesized that these children have some impairment in attending to emotional cues. based on this hypothesis, we conducted this study to evaluate visual directions of children with adhd towards paired emotional scenes.thirty boys between the ages of 6 and 11 ye...