background, aims, methods, results) max 200 words: When studying how a response variable depends on an explanatory variable it is convenient to create pairs of matched observations, i.e. pairs consisting of two observations that are homogenous, except for the studied explanatory variables and the response variable. So, the matching procedure is a method with the purpose to control for different...

Equation-based object-oriented (EOO) modeling languages such as Modelica provide a convenient, declarative method for describing models of cyber-physical systems. Because of the ease of use of EOO languages, large and complex models can be built with limited effort. However, current state-of-the-art tools do not provide the user with enough information when errors appear or simulation results a...

BACKGROUND The study aims to report the association between successful uveitis control following anti-tuberculous therapy (ATT) for uveitis associated with a positive tuberculosis (TB) screening test in a low endemic setting. A retrospective chart review of cases between 2010 and 2017 at a tertiary uveitis referral center in the United States of America was conducted. Subjects with any form of ...

Dynamic supination of the foot is a common residual deformity in children with clubfeet treated with the Ponseti method. Transfer of the anterior tibialis tendon (ATT) to the lateral cuneiform is an effective method for correcting this deformity when the cuneiform is ossified in children who are 3 to 5 years of age. We describe two cases of a previously unreported method of ATT transposition fo...

Regulated endocrine-specific protein, 18-kDa (RESP18), was previously cloned from rat neurointermediate pituitary based on its coordinate regulation with proopiomelanocortin and neuroendocrine specificity. RESP18 has no homology to any known protein. Although RESP18 is translocated across microsomal membranes after in vitro translation, AtT-20 pituitary tumor cells, which endogenously synthesiz...

In the early 1900s, the abnormal toxicity test (ATT) was developed as an auxiliary means to ensure safe and consistent antiserum production. Today, the ATT is utilized as a quality control (QC) release test according to pharmacopoeial or other regulatory requirements. The study design has not been changed since around 1940. The evidence of abnormal toxicity testing as a prediction for harmful b...

A bipartite enhancer sequence (composed of the O1 and O2 operator sites) is essential for assembly of the functional tetramer of phage Mu transposase (MuA) on supercoiled DNA substrates. A three-site interaction (LER) between the left (L) and right (R) ends of Mu (att sites) and the enhancer (E) precedes tetramer assembly. We have dissected the role of the enhancer in tetramer assembly by using...

AtT-20 cells, which produce beta-endorphin, and AtT-20/hENK cells, which are AtT-20 cells transfected with a proenkephalin gene, were implanted in the rat spinal subarachnoid space in an effort to produce an antinociceptive effect. Host rats were tested for antinociceptive activity by standard nociceptive tests, tail flick and hot plate. Although cell implants had minimal effect on the basal re...

Diabetes mellitus (DM) är en endokrin sjukdom hos katt, som är slående lik typ 2 diabetes hos människa. Katter och människor delar många riskfaktorer för sjukdomen, inklusive ett samband med insulinresistens kopplat till övervikt och en stillasittande livsstil. Det finns också patofysiologiska likheter, med förlust av β-celler och inlagring av amyloid i Langerhans öar i bukspottkörteln. En rasp...

This degree project was done at a development office at Ericsson AB in Göteborg in the autumn of 2008 and spring of 2009. At this office an application concept had been developed, this application was a graphical editor for creating and maintaining mobile portals, or mobile websites. This application had the form of a design sketch when the degree project started. The objectives of the degree p...