The phytochemical content of some Astragalus species distributed in Bulgarian flora has been previously studied. Among other compounds, flavoalkaloids, acylated flavonoids, flavonoid triglycosides and cycloartane saponins have isolated so far. composition the rest representatives this genus Bulgaria is not explored yet. aim study was to perform a screening for presence selected rare secondary m...

The antioxidant effect of aqueous-ethanolic extract from Astragalus glycyphylloides (Fabaceae), and its protection against carbon tetrachloride-induced hepatotoxicity were investigated in male Wistar rats. For seven consequent days the animals were treated orally with A. glycyphylloides extract (EAG) (100 mg/kg). Two hours after the last administration the animals were charged with carbon tetra...

We investigated the effects of Astragalus polysaccharide (APS) on palmitate-induced insulin resistance in C2C12 skeletal muscle myotubes. Palmitate-reduced glucose uptake was restored by APS. APS prevented palmitate-induced C2C12 myotubes from impaired insulin signaling by inhibiting Ser307 phosphorylation of insulin receptor substrate-1 (IRS-1) and increasing Ser473 phosphorylation of Akt. Mor...

Chromosome number and karyotype of Astragalus stereocalyx Bornm. (Milk-vetch) in the section Stereocalyx Bornm. distributing naturally in Turkey were analyzed in detail. This species is endemic to Turkey and growing in Eskişehir and Konya provinces. Squash preparation method was used for chromosome study in this species. The somatic chromosome number was determined as 2n = 16 in A. stereocalyx....

Some Chinese herbs are anti-thrombolysis, and anti-inflammatory, improves brain RNA content, promotes brain protein synthesis, enhances dopamine function, regulates brain hormones, and improves microcirculation in central nervous system that might improve, repair and rehabilitation from the stroke and brain injury. Specific Chinese herbs and their components, such as Acanthopanax, Angelica, cou...

BACKGROUND This study aims to investigate the leukogenic effect of astragalus polysaccharide (APS), to compare its effect of increasing the numbers of mature granulocytes with that of granulocyte colony-stimulating factor (G-CSF), and to investigate the mechanism. METHODS Rats were arbitrarily grouped into four groups (control, cyclophosphamide (CTX), CTX + APS, and CTX + G-CSF groups), and e...