A method for restoring an optical image which is subjected to low-pass frequency filtering is presented. It is assumed that the object whose image is restored is of finite spatial extent. The problem is treated as an algebraic image-restoration problem which is then solved as a quadratic programming problem with bounded variables. The regularization technique for the ill-posed system is to repl...

.................................................................................................................................................. 6 List of Figures ......................................................................................................................................... 7 Introduction to Dissertation ..................................................................

Hedgehog (Hh) proteins belong to a class of morphogens involved in many biological processes during embry-onic development; they are relatively silent during normal adult life although they may be recruited postnatally in re-sponse to tissue injury. Three secreted proteins have been identified: Sonic hedgehog (Shh), Desert hedgehog and Indianhedgehog. The interaction of Hh ligand wi...