Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease caused by the accumulation of large amounts of fat in the hepatocytes. Given that atorvastatin is effective for treatment of NAFLD, the present study investigated effects of high-fat/fructose diet (HFFD) with atorvastatin on liver enzymes and lipid profile in a NAFLD rat model. Methods: Thirty-two m...

the aim of this study was to investigate c-reactive protein (crp) level in preeclampsia (pe) and its association with the severity of the disease. this cross-sectional study included 43 women with mild pe, 43 women with severe pe, and 43 healthy pregnant. they were selected in the third trimester of pregnancy in the afzalipour hospital, kerman, iran, from march 2006 to march 2007. mean diastoli...

The isoenzymes of aspartate transaminase differ in their kinetic properties in that the cytoplasmic isoenzyme is more readily inhibited by adipate and by 2-oxoglutarate (substrate) at low pH. A differential kinetic assay based on this phenomenon has been optimised for use in assays of serum samples. The new method agrees well with an immune absorption procedure. Methods based on chromatographic...

Objectives: To contribute to case management algorithms and guidelines by evaluating the clinical symptoms, laboratory data, risk factors mortality rates of patients admitted health institutions with tick bite in Tokat. 
 Methods: The virus determination was made from blood conventional PCR 141 patient. Epidemiological data such as socio-demographic variables were compared biochemical hema...

For the common rs738409 C>G SNP, which is located in the patatin-like phospholipase domain-containing protein 3 (PNPLA3), a strong association between non-alcoholic fatty liver disease (NAFLD) has been detected [1], approved [2-8] and expanded to an association with liver-fat content in general [8-13] and serum transaminase levels [14]. Also an association to a higher risk of progression to cir...

Mild elevations in liver chemistry tests such as alanine transaminase and aspartate transaminase can reveal serious underlying conditions or have transient and benign etiologies. Potential causes of liver transaminase elevations include viral hepatitis, alcohol use, medication use, steatosis or steatohepatitis, and cirrhosis. The history should be thorough, with special attention given to the u...

Stress controls the expression of a cohort of genes. Among these, the glucose-regulated protein (GRP) genes are specifically activated by glucose deprivation, reducing agents, glycosylation block, intracellular calcium or ex vivo incubations of tissues or cells. We demonstrate that these stimuli induce the expression of the cytosolic aspartate aminotransferase gene in adipocytes by a process in...

The levels of creatine kinase, hydroxybutyric dehydrogenase, and aspartate transaminase have been serially measured in the serum of patients undergoing surgery. Serum enzyme levels often rose to a range commonly found after myocardial infarction but fell to normal within 5-10 days. Raised serum enzyme levels have no diagnostic significance in a case of postoperative chest pain until after the f...