To date, no attempt has been made to study alterations occurring in the amino acid profile in chronic models of thioacetamide-induced liver cirrhosis. In this work, changes in serum amino acids and proteins in rats with thioacetamide-induced liver cirrhosis are reported, together with changes in enzyme activities in the liver and serum. Seventeen female Wistar rats were used. Eight rats were gi...

Acute lymphoblastic leukemia (ALL) in adults is a relatively rare malignancy. The typical presentation includes signs and symptoms associated with bone marrow failure, including fevers, infections, fatigue, and excessive bruising. In this article, we report an unusual systemic presentation of ALL in a previously healthy 18-year-old man. He initially presented with several-day history of nausea ...

background: increasing evidence suggests an association between ele­vated serum aminotransferase levels and metabolic disorders (metabolic syndrome, hyperlipemia and diabetes mellitus). however, the significance of relatively low levels of aminotransferases in relation to metabolic disorders has not been fully investigated in the general population. we inves­tigated the association between seru...

Abstract Background Drug-induced hepatotoxicity is one of the most important causes liver dysfunction. Acetaminophen (paracetamol) an analgesic-antipyretic drug generally considered safe but its overdose may cause toxicity. Marine macro-algae (seaweeds) especially brown seaweeds possess unique biological activities including hepatoprotective potential. The current study focused on effect differ...

D-galactosamine is a hepatotoxic agent, which induces diffuse injury of liver tissue followed by the regeneration process. Our data showed a high increase of serum aminotransferases after D-galactosamine administration, which indicates a high extent of liver injury. When lipid emulsion was applied immediately after D-galactosamine, the increase of serum aminotransferases was greatly reduced. In...

previous studies indicated that endurance exercise decreases levels of liver enzymes. the aim of this study was to determine the effect of endurance exercise on liver enzymes in eight weeks in iranian women who are stopping the drug with methadone. sixty iranian women prisoners including 30 cases as experimental group and 30 volunteers served as control. the mean age, height, weight, percent of...

Aminotransferases (ATs) are pyridoxal 5′-phosphate-dependent enzymes that catalyze the reversible transfer of an amino group from donor to a keto substrate. ATs promising biocatalysts replacing traditional chemical routes for production chiral amines. In this study, in silico-screening metagenomic library isolated Curonian Lagoon identified 11 full-length fold type IV aminotransferases were suc...