Background: Overconsumption of added sugars, particularly refined has been shown to be associated with adverse health concerns. Aim: The present study aimed elaborate calorie-reduced marmalades nutritional benefits as well satisfactory sensory properties, in order reduce sugar intake without compromising consumers' acceptance. Materials and methods: Two formulas sugar-reduced were elaborated by...

In the November issue of Environmental Health Perspectives, Apelberg et al. (2007) reported an inverse relationship between umbilical cord blood concentrations of perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) and ponderal index and head circumference in children delivered vaginally in Baltimore, Maryland. In the same issue, Fei et al. (2007) reported an inverse relationship bet...

This study was carried out to disclose effects generated by the uncoupling of the sensory and energetic components of sweet solutions. A comparison was made between equi-sweet preloads of three intense sweeteners (saccharin, aspartame and acesulfame-K), a bulk sweetener (glucose) and a nonsweet water control. Measures were made of subjective ratings of motivation to eat, food preferences and en...

In last few years transporter targeted drug delivery has drawn attention of research to identify and explore various nutrient transport systems including amino acid transporters for better drug delivery. The aim of the present study was to investigate and characterize the transport of L-phenylalanine across goat cornea. Transport of Lphenylalanine (0.5 % w/v aqueous solution) through excised go...

In the pharmaceutical industry, there are increasing requirements for analytical methods in quality assessment for the production of drugs. In this investigation, ion mobility spectrometry (IMS) was used for the rapid qualitative separation and identification of active ingredients in generic over-the-counter drugs and food additives in beverages. The active ingredients determined in drugs were ...

BACKGROUND The role of sweeteners on cancer risk has been widely debated over the last few decades. To provide additional information on saccharin and other artificial or low-calorie sweeteners (mainly aspartame), we updated the analysis of an integrated network of case-control studies conducted in Italy between 1991 and 2004 including data on cancers of the stomach, pancreas, and endometrium. ...

An integrated solid-phase spectrophotometry-FIA method is proposed for simultaneous determination of the mixture of saccharin (1,2-benzisothiazol-3(2H)-one-1,1-dioxide; E-954) (SA) and aspartame (N-L-alpha-aspartyl-L-phenylalanine-1-methyl ester; E-951) (AS). The procedure is based on on-line preconcentration of AS on a C18 silica gel minicolumn and separation from SA, followed by measurement, ...

¹H Nuclear magnetic resonance (NMR) spectroscopy (400 MHz) was used in the context of food surveillance to develop a reliable analytical tool to differentiate brands of cola beverages and to quantify selected constituents of the soft drinks. The preparation of the samples required only degassing and addition of 0.1% of TSP in D₂O for locking and referencing followed by adjustment of pH to 4.5. ...

Glycation is a non-enzymatic reaction between the carbonyl groups of sugars and the amino groups of proteins, nucleic acids and lipids. This process results in the formation of early glycation products, which rearrange to form more stable advanced glycation end products (AGEs). Glycation has been linked to a number of diseases such as, Alzheimer’s, diabetes mellitus, cataract, Parkinson’s, phys...