the liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. for example the liver is, extremely sensitive to changes in insulin or glucagon levels. the liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. chr...

The epithelial Na(+) channel (ENaC) is typically formed by three homologous subunits (alpha, beta, and gamma) that possess a characteristic large extracellular loop (ECL) containing 16 conserved cysteine (Cys) residues. We investigated the functional role of these Cys residues in Na(+) self-inhibition, an allosteric inhibition of ENaC activity by extracellular Na(+). All 16 Cys residues within ...

BackgroundOvarian reserve and normal oocyte ploidy are inversely correlated to maternal age. However, the effects of ovarian aging on blastocyst conversion rates is not clearly described in literature. Age-specific data this topic would be useful when counseling patients after an embryo cryopreservation cycle.ObjectiveTo determine blastulation cycles which yield at least one cryopreserved usabl...

It was previously shown that costimulation of CD8(+) lymphocytes results in de novo expression of CD4. This study expanded on this observation to investigate the function of CD4 on CD8 cells. The ability of costimulated CD8 cells to respond to interleukin 16 (IL-16), a ligand that binds CD4 and induces cellular chemotaxis, was examined. IL-16-mediated ligation of CD4 expressed on CD8 T cells wa...

Th e aim of the study was to analyse the changes in BMI category between 7 and 16–18 years of age on the basis of continuous studies and evaluate which factors are related to the increase and decrease in BMI category. Data were collected from 1008 secondary school students aged 16–18 y. Body height and weight were measured and BMI was calculated. Information on height and body mass in earlier p...