The synthesis of blood group ABH antigens is under genetic control, where the primary gene products are glycosyltransferases. Several studies have demonstrated cancer-associated alterations in ABH antigen expression in human colon cancer tissues. However, the mechanism(s) responsible for these alterations has not been elucidated. Therefore, experiments were conducted using nine established colo...

BACKGROUND In The Netherlands, caesarean sections (CSs) are rarely combined with tubal occlusion (TO), partly because discussing CS/TO near delivery is considered unethical and earlier hypothetical counselling--i.e. suppose you happen to need a CS--is rare. This results in more unintended pregnancies and is inconsistent with informed choice. We explored whether TO should indeed not be made rout...

Mammalian thioredoxin reductases (TrxR) are homodimers, homologous to glutathione reductase (GR), with an essential selenocysteine (SeCys) residue in an extension containing the conserved C-terminal sequence -Gly-Cys-SeCys-Gly. In the oxidized enzyme, we demonstrated two nonflavin redox centers by chemical modification and peptide sequencing: one was a disulfide within the sequence -Cys(59)-Val...

S OF RECENT SCIENTIFIC PUBLICATIONS BY THE STAFF OF N.V. PHILIPS' GLOEILAMPENFABRIEKEN Reprints of these papers not marked with an asterisk"' can be obtained free of charge upon application to the Philips Research Laboratory, Eindhoven, Netherlands. 2568*: H. Bremmer: Comparaison des fluctuations de l'amplitude et de la phase des champs engendrés par diffusion (champs de turbulence) (Onde élect...

Joint Mass Spectrometry Centre, Chair of An University of Rostock, 18059 Rostock, Germa de; Tel: +49 381 498 6536 Joint Mass Spectrometry Centre, Cooper Analytics (CMA), Helmholtz Zentrum M Environmental Health (GmbH), Ingolstäd Germany Biological Oceanography, Leibniz Instit Warnemünde-Rostock, Germany Marine Chemistry, Leibniz Institute for Ba Rostock, Germany † Electronic supplementary infor...

STRUCTURE AND FUNCTION OF SODIUM CHANNEL SUBUNITS .. . . . . . . . . . 495 Purification and Characterization ....... , . . . . . . . . .. . . . . . . . . . . . . . . . . . . .. . . . 495 Cloning and Primary Structure of the Sodium Channel a Subunit. . . . . . . . . . . . . . . 496 Cloning and Primary Structure of the {Jl and {32 Subunits. . . . . . . . . . . . . . . . . . . . . 498 Functional R...

The acivity-guided fractionation upon the MeOH extract of the aerial parts ofSorbaria sorbifolia var.stellipila led to the isolation of two cucurbitacin-compounds, cucurbitacin D and cucurbitacin F, as active principles. Two compounds were shown to exhibit significant cytotoxicity against cultured human tumor cell lines, A-549, SK-OV-3, SK-MEL-2, XF-498, and HCT 15.

Abstract Introduction In modern medicine, free flap reconstruction has become the gold standard when faced with soft tissue defects. The impressive cosmesis, and adaptability of flaps means that we can securely state are in era Plastic Surgery defined by reconstruction. However, as part reconstruction, clinical monitoring is a central tenet post-operatively. Different departments have different...