The coefficient of plasma protein entry into the aqueous humor, kin, was calculated in the human eyes from the aqueous protein concentration measured with a flare-cell meter and from the aqueous flow rate determined with fluorophotometry. The value of kin averaged 3.47 +/- 0.25 x 10(-5) min-1 (mean +/- SEM) in 12 eyes of six normal young volunteers. The time course of changes in aqueous protein...

LDH activity was determined in aqueous humour samples from 11 eyes (of 10 children), four of which contained retinoblastoma. Simultaneous serum LDH levels were also determined in eight of the children. There was no correlation between serum and aqueous humour LDH activity. Total aqueous humour LDH activity ranged from 0 to 99 i.u/l. in the seven eyes with non-neoplastic conditions. It was 56, 1...

BACKGROUND The aim of the paper is to present the Polish adaptation of the Humor Climate Questionnaire (HCQ), designed to measure humor as organizational climate feature. MATERIAL AND METHODS The authors employed back-translation and independent judges method to choose the best version of the translated items. The psychometric properties of HCQ were estimated on the basis of 2 samples: the ba...

The experimental research that looks into the effects of political humor on an individual's attitudes toward politics and politicians does not evaluate its long-term effects. With this in mind, this study aims to determine the possible effects that being exposed to humor which belittles politicians may have on an ordinary citizen's trust in them, while at the same time it observes the possible ...

purpose : to investigate the penetration of cefixime and ciprofloxacin to the rabbit eye on the basis of microbial inhibition of aqueous and vitreous humour after oral administration. methods : in this experimental study, 36 rabbits (72 eyes) were randomly divided into two groups group a consisted of 20 rabbits and group b 16 rabbits. each group was divided into four equal subgroups. the rabbit...

background: immune reactions have been reported to be involved in the destruction of retinal ganglion cells (rgcs) in glaucoma. objective: to investigate the role of major histocompatibility complex class i-related chain a and b (mica and micb) molecules in the pathogenesis of glaucoma. methods: aqueous humor and serum samples from 15 glaucoma patients and 45 patients with cataract, undergoing ...

KNOWLEDGE of the means by which substances enter and leave the eye, usually referred to as " aqueous-humour dynamics ", is essential for an understanding of the factors contributing to the control of the intra-ocular pressure. In non-living systems, when a membrane separates two concentrations of a substance in a solution to which the membrane is permeable, this substance travels across the mem...

A group of 26 subjects with myotonic dystrophy were studied with fluorophotometry to evaluate the relationship between aqueous humor dynamics and the hypotony found in this disorder. All 26 received topical fluorescein to determine the anterior chamber elimination coefficient; five received systemic fluorescein to evaluate the integrity of the blood-aqueous barrier. The group has a mean intraoc...

The aim of this study was to increase bioavailability of the antiviral drug acyclovir (ACV) when administered by the ocular route. For this purpose, a new lipophilic derivative of acyclovir was synthesized, both possessing greater lipophilicity and providing the formation of a homogeneous water dispersion with higher amount of ACV than the aqueous solution of the parent drug. This was done by c...

Certain forms of glaucoma are associated with displacement of the iris from its normal contour. We present here a mathematical model of the coupled aqueous humor-iris system that accountsfor the contribution of aqueous humor flow and passive iris deformability to the iris contour. The aqueous humor is modeled as a Newtonian fluid, and the iris is modeled as a linear elastic solid. The resulting...