The aim of this study is to determine the effect of methanol crude leaves extract and aqueous fraction of Acacia nilotica on liver enzymes and lipid profiles of alloxan induced diabetic Wistar rats. Diabetes was induced by a single intraperitoneal injection of alloxan dissolved in 0.9%v/v cold normal saline solution at a dose of 150 mg/kg body weight, after which the rats were randomly divided ...

AIMS Atrial fibrillation (AF) is a common complication in patients with acute myocardial infarction and is associated with an increase in the risk of death. The excess mortality associated with AF complicating acute myocardial infarction has not been studied in detail. Observations indicate that AF facilitates induction of ventricular arrhythmias, which may increase the risk of sudden cardiovas...

An artificial neural network (ANN) model was designed to predict the tensile properties in high-strength, low-carbon bainitic steels with a focus on fraction of constituents such as PF (polygonal ferrite), AF (acicular GB (granular bainite), and BF (bainitic ferrite). The input parameters were constituents, while output composed yield strength, yield-to-tensile ratio, uniform elongation. ANN ex...

Hypertriglyceridemia is an independent risk factor for atherosclerosis. This risk is most likely due to accumulation of circulating triglyceride rich lipoproteins with heterogeneous particles. The identification and characterization of these triglyceride rich lipoproteins is important to detect abnormality of triglyceride metabolism. In the present study, we developed a new method that combines...

The present study provides evidence of the anti-asthmatic signaling activity of an aqueous fraction of green tea using specific in vitro and in vivo assays in an ovalbumin-induced asthmatic model. Mice sensitized to ovalbumin were orally administered an aqueous extract of Camellia sinensis. The lungs of these mice were then examined by hematoxylin and eosin staining and ELISA analysis to measur...

Previous studies have demonstrated that patients with atrial fibrillation (AF) and heart failure preserved ejection fraction (HFpEF) may develop the latter. The prevalence of 20-43% for AF in HFpEF 50- 60% patients. pathophysiology indicates usually precedes HFpEF, but each disease can promote progression other one. Multiple mechanisms been posited, such as left (LA) fibrosis myopathy well volu...

the effects of three ficus carica leaf extracts on the total cholesterol levels (tc) of serum and liver were investigated in experimentally-induced nutritional hyperlipidemic rats. in nine treatment groups (n=5 each group), hyperlipidemic rats were treated daily with hydromethanolic (total) extract (2.5, 5, 10 mg/kg, intraperitoneal [ip]) and its aqueous fractions, namely fraction a (10, 50, 25...

BACKGROUND Myrtus communis L. has a folkloric repute for the management of diarrhea and dysentery in different parts of the world. However, the safety and efficacy of the leaf extract have not been scientifically validated in animal model. This study was, therefore, aimed to investigate the antidiarrheal effect of 80% methanol extract (80ME) and solvent fractions of the leaves of Myrtus communi...

Introduction. Catharanthus roseus (L.) is used in some countries to treat diabetes. The aim of this study was to evaluate the hypoglycemic activity of extracts from the flower, leaf, stem, and root in normal and alloxan-induced diabetic mice. Methods. Roots, leaves, flowers, and stems were separated to obtain organic and aqueous extracts. The blood glucose lowering activity of these extracts wa...

BACKGROUND Atrial fibrillation (AF) and heart failure with reduced ejection fraction frequently coexist. The AATAC (Ablation versus Amiodarone for Treatment of persistent Atrial fibrillation in patients with Congestive heart failure and an implantable device) trial suggests that catheter ablation may benefit these patients. However, applicability to contemporary ambulatory cardiology practice i...