OBJECTIVES The purpose of this study was to examine the renal effects of a V2 receptor arginine vasopressin (AVP) antagonist in heart failure. BACKGROUND Arginine vasopressin has been implicated in the renal water retention and dilutional hyponatremia associated with chronic heart failure. METHODS We examined the effects of the oral, non-peptide, selective V2 receptor antagonist lixivaptan ...

conclusions our findings revealed that aerobic exercise increases self-esteem. an improvement in educational, family, social, and general self-esteem scores was seen only in the experimental group. results the results showed that although the self-esteem average score was not significant before the intervention, it increased significantly in the experimental group. in the experimental group, th...

a series of 2-amino-4-aryl-3-cyano-7-(dimethylamino)-4 h -chromenes was synthesized by condensation of 3-(dimethylamino)phenol, an aromatic aldehyde and malonitrile in ethanol containing piperidine. the assignments of the structure of all synthesized compounds were based on spectral data (ir, mass and 1 h nmr). the cytotoxic activities of the synthesized compounds against six human tumor cell l...

background: little in known regarding the clinical relevance of sirt1 in multiple sclerosis (ms).   here, we aimed to evaluate mrna expression, protein level and enzyme activity of sirt1 in peripheral blood mononuclear cells (pbmcs) isolated from relapsing –remitting ms patients (rrms) and healthy controls. materials and methods: twenty patients with rr-ms and twenty two age- and sex-matched he...

background: although various surface disinfectants have been introduced, most of them are toxic. the use of natural antimicrobial agent e.g. phytol, extracted from leptadenia pyrotechnica is a new strategy. the aim of this study was to evaluate the antimicrobial activity, toxicity, and stability of phytol. methods: the serial concentrations of phytol were prepared, and separately incubated with...

the antimicrobial activity of methanolic extracts from different parts of 11 indigenous wild plantspecies used in traditional medicines of iran were tested against nine species of microorganisms: escherichiacoli, staphylococcus aureus, staphylococcus epidermis, pseudomonas aeruginosa, klebsiella pneumoniae,salmonella typhi, bacillus subtilis, aspergillus niger and candida albicans. the antimicr...

substituted schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. on cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...