The classification of benign sebaceous neoplasms has been challenged both by the assertion that sebaceous adenomas are really carcinomas and by difficulties in drawing the boundaries between sebaceomas and other lesions. We performed a clinicopathologic study of 30 cases of basaloid neoplasms with sebaceous differentiation, excluding cases of definite sebaceous carcinoma with severe nuclear aty...

luteal hidradenitis suppurativa (HS) is an acute, subacute, or chronic infection that affects the sudoriparous, apocrine, eccrine, or pilosebaceous apparatus of the affected area. Although its pathophysiology is poorly understood, it is generally believed that obstruction of the apocrine pores results in glandular dilatation and bacterial superinfection, with subsequent gland rupture disseminat...

Apocrine glands are the major type of sweat gland in dogs, and distribution of eccrine sweat glands is limited to footpad (Goldschmidt and Shofer, 1992). Apocrine sweat gland tumors are rather common in dogs and tend to occur on the head, neck and limbs. The Golden Retriever is a breed that shows a predisposition to such tumors (Kalaher et al., 1990). The tumor was greatly resembles its human c...

Apocrine differentiation was an incidental finding in an ovarian cyst. This is considered to be a further example of Müllerian metaplasia that has not been described before and which, theoretically, could occur in any organ of Müllerian derivation (ovary, uterus, cervix or fallopian tube). It is suggested that sites of such metaplasia could in turn be the origin of primary apocrine carcinoma in...

The Spitz nevus was first described as the “melanoma of childhood” or “juvenile melanoma” by Sophie Spitz in 1948 (1). Most spitzoid melanocytic proliferations can be classified as benign Spitz nevi or spitzoid melanomas based on published criteria (2-3). However, a subset of spitzoid lesions have histological features that deviate from a typical Spitz nevus, yet are insufficient for a definiti...

Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from ...

Because spitzoid melanoma shares many histopathologic features with Spitz nevus, it is one of the most difficult lesions to diagnose in dermatopathology. Uncertainty exists in the medical literature about how to diagnose melanocytic proliferations including Spitz nevus and spitzoid melanoma. A misdiagnosis of a melanoma as Spitz nevus is one of the most frequent causes of malpractice lawsuits i...

The paper presents the coexistence of a nevus flammeus and basal cell carcinoma affecting the left upper lid of 61-year-old farmer with Sturge-Weber syndrome. The occurrence of basal cell carcinoma in nevus flammeus is extremely rare. The etiology of the malignancy in this situation is unknown. It is difficult to diagnose neoplastic transformations that could arise in the nevus flammeus. Radiot...

A 19-year old female with blue rubber bleb nevus syndrome. Endoscopic laser photocoagulation and surgical resection of gastrointestinal angiomata. cerebellum: a case report and review of the literature. 39. Hofhuis WJD, Orange AP, Bouquet J, et al. Blue rubber blue nevus syndrome: report of a case with consumption coagulopathy complicated by manifest thromboses. A case report: pregnancy complic...