BACKGROUND Apoptotic microparticles are responsible for almost all tissue factor activity of the plaque lipid core. We hypothesized that elevated levels of procoagulant microparticles could also circulate in the peripheral blood of patients with recent clinical signs of plaque disruption and thrombosis. METHODS AND RESULTS We studied 39 patients with coronary heart disease, including 12 patie...

 The crystal structure of two B-type carbonated apatite samples was re-analyzed, using the data of Wilson et al (2006). By applying the least squares method for the determination of carbon and oxygen atoms, a slightly different result was obtained, suggesting that the carbonate ion is not rigorously planar. Keywords Carbonated apatite, Carbonate, Xray diffraction.

I report experimental and numerical studies of microparticle motion in a dusty plasma. These microparticles are negatively charged and are levitated in a plasma consisting of electrons, ions and neutral gas atoms. The microparticles repel each other, and are confined by the electric fields in the plasma. The neutral gas damps the microparticle motion, and also exerts random forces on them. I in...

DOI: 10.1002/admt.201700177 organisms. The manipulation of superparamagnetic microparticles, in particular, has a wide range of applications, including magnetic logic;[13] sorting and trapping of magnetically tagged proteins,[14] cells,[15] and microorganisms;[16] microfluidic mixing;[17] magnetoresistive biosensing;[18] immunoassays;[19] and lab-on-a-tube devices.[20] In principle, the manipul...

This experiment was conducted for evaluating the humoral immune responses induced by Poly Lactide-co-Glycolide Acid (PLGA) microspheres coupled inactivated Newcastle Disease Virus (NDV) vaccine in comparison to an ‘in-house’ prepared inactivated and a live commercial vaccine. PLG microparticles containing inactivated NDV were prepared by a double emulsion technique based on solvent evaporation ...

Rats were raised on a variety of isotopically controlled diets comprising 20% C3, C4 or marine protein and C3 and/or C4 non-protein or energy (i.e. sucrose, starch and oil) macronutrients. Compound specific stable carbon isotope ( C) analysis was performed on the cholesterol isolated from the diet (n 7) and bone (n 15) of these animals and the values compared with bulk C measurements of bone co...

Unraveling the mechanisms behind the processes of cell attachment and the enhanced proliferation that occurs as a response to the presence of calcium silicate-based materials needs to be better understood so as to expand the applications of silicate-based materials. Ions in the environment may influence apatite precipitation and affect silicate ion release from silicate-based materials. Thus, t...

The differentiation of stem cells into multi-lineages is essential to aid the development of tissue engineered materials that replicate the functionality of their tissue of origin. For this study, Raman spectroscopy was used to monitor the formation of a bone-like apatite mineral during the differentiation of human mesenchymal stem cells (hMSCs) towards an osteogenic lineage. Raman spectroscopy...

BACKGROUND Sickle cell disease is characterized by a hypercoagulable state as a result of multiple factors, including chronic hemolysis and circulating cell-derived microparticles. There is still no consensus on the cellular origin of such microparticles and the exact mechanism by which they may enhance coagulation activation in sickle cell disease. DESIGN AND METHODS In the present study, we...

Kafirin microparticles have potential as colon-targeted delivery systems because of their ability to protect encapsulated material from digestive processes of the upper gastrointestinal tract (GIT). The aim was to optimize prednisolone loading into kafirin microparticles, and investigate their potential as an oral delivery system. Response surface methodology (RSM) was used to predict the optim...