Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial pneumonia. To characterize pathogen-derived and host-related factors in intensive care unit (ICU) patients with MRSA pneumonia, we evaluated the Improving Medicine through Pathway Assessment of Critical Therapy in Hospital-Acquired Pneumonia (IMPACT-HAP) database. We performed multivariate regression analyses of 2...

Background & Aims: Exposure Keratitis (EK) is a common problem in critically ill patients admitted to the Intensive Care Unit (ICU). We conducted exposure keratitis in mechanical ventilatory patients in the intensive care unit of Imam Khomeini Hospital in Urmia for five years. Materials & Methods: In this retrospective cross-sectional study, the records of the patients were taken from the medi...

Aim & Objectives: Prospective study to evaluate the mortality prediction in patients with perforation peritonitis using APACHE II, SAPS II, MODS, SOFA and MPI scoring systems. Material and Methods: One hundred patients of hollow viscus perforation peritonitis, from October 2012 – June 2014, were evaluated preoperatively using above mentioned scores and outcome noted in terms of mortality; there...

Elderly patients in the USA account for 26-50% of all intensive care unit (ICU) admissions. The applicability of validated ICU scoring systems to predict outcomes in the "Oldest Old" is poorly documented. We evaluated the utility of three commonly used ICU scoring systems (SAPS II, SAPS III, and APACHE II) to predict clinical outcomes in patients > 90 years. 1,189 surgical procedures performed ...

Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play important roles in autoimmunity, infectious diseases and cancers. However, little is known about the roles of these invariant T cells in multiple trauma. The purposes of this study were to examine MAIT and NKT cell levels in patients with multiple trauma and to investigate potential relationships betw...

We aimed to investigate the efficacy of four severity-of-disease scoring systems in predicting the 28-day survival rate among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) requiring emergency care. Clinical data of patients with AECOPD who required emergency care were recorded over 2 years. APACHE II, SAPS II, SOFA, and MEDS scores were calculated from sever...

  Background: There are challenges ahead of short-term hospitalization of low-risk patients hospitalized only for monitoring of severe disease who may die soon after admission. The purpose of this study was to suggest strategies for the management of ICU stay lengths and to ensure optimal use of ICU resources.   Methods: The study was conducted retrospectively on 246 patients admitted to 9 gene...

In 35 patients fulfilling the criteria of systemic inflammatory response syndrome (SIRS) of infectious origin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), tumor necrosis factor-soluble receptor (TNF-sR), and interleukin-12 (IL-12), C-reactive protein (CRP) levels and the Acute Physiology, and Chronic Health Evaluation III score (APACHE III) were determined on days 1 to 7, 14,...

Methods Prospective observational study. Plasmatic levels of ProADM, C reactive protein (CRP) and procalcitonin (PCT) and lactate in 110 consecutive patients admitted to ICU with severe sepsis / septic shock at days 1, 3 and 7 after admission. Clinical and demographic data: age, gender, comorbidities, APACHE II and SOFA scores. Recruited period over 12 months. Statistical analysis: c test for c...