Nanomedicine opens new therapeutic avenues for attacking viral diseases and for improving treatment success rates. Nanoparticulate-based systems might change the release kinetics of antivirals, increase their bioavailability, improve their efficacy, restrict adverse drug side effects and reduce treatment costs. Moreover, they could permit the delivery of antiviral drugs to specific target sites...

The ultimate goals of treating chronic hepatitis B (CHB) is prevention of hepatocellular carcinoma (HCC) and hepatic decompensation. Since the advent of effective antiviral drugs that appeared during the past two decades, considerable advances have been made not only in controlling hepatitis B virus (HBV) infection, but also in preventing and reducing the incidence of liver cirrhosis and HCC. F...

Trifluorothymidine (TFT) and adenine arabinoside (ara-A) are effective antiviral drugs with a very low toxicity for the cornea. In our study no difference between these 2 drugs in antiviral activity was noted. The average healing time for TFT was 11-14 days and for ara-A 10-54 days. These data differ markedly from those of other studies. This was the result of the use of additional criteria for...

Japanese encephalitis a mosquito transmitted viral disease is a global confront for public health. The disease is a pediatri problem, the seriousness of the disease can be predicted as it mostly affects the children and the survivor are left with ser long term neuropsychiatric problems. Hence the disease is affecting our future generation. The only available option to control JE is vaccination ...

Hepatitis C virus infection is one of the main causes of chronic liver disease worldwide. Until recently, the standard antiviral regimen for hepatitis C was a combination of an interferon derivative and ribavirin, but a plethora of new antiviral drugs is becoming available. While these new drugs have shown great efficacy in clinical trials, observational studies are needed to determine their ef...

Hepatitis C virus (HCV) is a positive single-stranded RNA virus of enormous global health importance, with direct-acting antiviral therapies replacing an immunostimulatory interferon-based regimen. The dynamics of HCV positive and negative-strand viral RNAs (vRNAs) under antiviral perturbations have not been studied at the single-cell level, leaving a gap in our understanding of antiviral kinet...

background herpes simplex virus 1 (hsv-1) resistance to drugs and the side effects of drugs have drawn the attention of investigators to herbal plants. objectives the main aim of the current research was to investigate the effects of glycyrrhiza glabra (liquorice root) on hsv-1. one of the objectives of the current research was to determine the efficacy and the effect of the elapsed incubation ...

Abstract: Influenza virus is the most important cause of annual morbidities and mortalities worldwide with numerous antigenic drifts and shifts. Inaccessibility to effective drugs and vaccines has made world health authorities to be interested in traditional medicine in order to prevent spread of the infectious agent. Garlic is one of the most famous of all plants in human history. It has bee...

Pulmonary arterial hypertension is a condition characterized by an increase in mean pressure the pulmonary artery. This pathology associated with high mortality, and specific therapy for does not affect cause of disease extremely expensive. In this regard, it especially important to study modifiable etiological factors hypertension. One such factor drugs. leading groups drugs-inductors anorexig...