BACKGROUND The spread of antimicrobial resistance in developing countries is associated with complex and interconnected factors, such as excessive and unnecessary prescribing of antimicrobials, increased self-prescribing by the people and poor quality of available antimicrobials. Moreover, the failure to implement infection control practices and the dearth of routine susceptibility testing and ...

The objective of this study was to establish a repeatable, standardized laboratory procedure for monitoring the development of antimicrobial resistance in bacteria isolated from animals and food of animal origin in South Africa, with reagents prepared in-house. The emergence of resistance and the spread of resistant bacteria can be limited by implementing a veterinary antimicrobial drug policy,...

For decades, fungi have been the main source for the discovery of novel antimicrobial drugs. Recent sequencing efforts revealed a still high number of so far unknown "cryptic" secondary metabolites. The production of these metabolites is presumably epigenetically silenced under standard laboratory conditions. In this study, we investigated the effect of six small mass chemicals, of which some a...

OBJECTIVES The aim of this study was to investigate antimicrobial prescribing in nursing homes in countries across Europe. METHODS Point prevalence studies were completed in April and November 2009 in 85 nursing homes in 15 European countries and two UK administrations. RESULTS A total of 10,388 and 9430 residents participated in April and November 2009, respectively. The mean prevalence of...

Dental caries is a multifactorial infectious disease that leads to the destruction of dental hard tissue. The main goal of research into medicinal plants is to seek compounds with antimicrobial activity for subsequent use in prevention strategies and control of infectious diseases. The aim of this study was to evaluate the antimicrobial activity of fractions and subfractions obtained from Elaea...

background and objectives: the appearance of antibiotic resistance in streptococcus pneumoniae has raised a global concern over the past three decades. this study was conducted to determine the antimicrobial susceptibility of s. pneumoniae isolated from patients in children´s medical center (cmc) hospital during 2001 to 2011. materials and methods: during the 11 years period, a total of 194 s. ...

abstract         background and objective: lactic acid bacteria are gram-positive, catalase-negative, nonsporulating, either rod- or coccus-shaped bacteria that have beneficial effects on their hosts by producing antimicrobial substances such as lactic acid, hydrogen peroxide, bacteriocins and biosurfactants. bacteriocins are antimicrobial peptides that are produced by bacteria and can inhibit ...

Bacteria subvert the immune system by suppressing antimicrobial responses or directly killing immune cells. A new study shows that Staphylococcus aureus can also turn antimicrobial responses to its advantage by converting neutrophil extracellular traps into a bacterial weapon against macrophages.

  Background: The spread of pathogenic microorganisms in food and beverage and their resistance to antibiotics have raised major concerns for public health. The aim of this study was to investigate the antimicrobial activity of various metal oxide nanoparticles (NPs) including zinc oxide (ZnO), magnesium oxide (MgO), and iron oxide (Fe2O3) NPs against Staphylococcus aureus (S. aureus) and Esch...