BACKGROUND There is considerable interest in the expression of cancer testis (CT) antigens in human cancers, because they may serve as the basis for diagnostic tests or an immunologic approach to therapy, or as prognostic markers. METHODS On this basis, we evaluated by semiquantitative reverse-transcriptase polymerase chain reaction (RT-PCR) the expression of genes that code for tumor antigen...

background and aims: influenza (flu) is a respiratory infection in mammals and birds. it is caused by an rna virus in the family orthomyxoviridae. the virus is divided into three main types. influenza virus type a is found in a wide variety of bird and mammal species and can undergo major shifts in immunological properties. hemagglutinin (ha) is an important influenza virus surface antigen that...

introduction: neisseria meningitidis is a major causative agent of bacterial septicemia and meningitis in human. pora is a major component of the outer membrane of n. meningitidis and functions as a cationic porin. this study aimed to clone and determine the expression of pora as the first step for producing a proper antigen in a vaccine study against n. meningitidis. methods: an approximately ...

it has recently been shown that ror1, a member of the receptor tyrosine kinase family, is overexpressed in leukemic b cells of chronic lymphocytic leukemia (cll) and a subset of acute lymphoblastic leukemia (all). in this comparative study the expression profile of ror1 mrna was investigated in iranian patients with cll and acute myelogenous leukemia (aml) and the results were compared with tho...

background and aims. vascular endothelial growth factor (vegf) and ki-67 antigen are contributing factors in this process cell proliferation and new blood vessels formation in tumor progression. this study was conducted to examine the relationship between the expression of vegf and ki-67 and gender and age of patients with oral squamous cell carcinoma (oscc). materials and methods. twenty-three...

UVB irradiation is a commonly used therapy for inflammatory skin diseases, which has been known to attenuate immune responses partly via the induction of CD4+Foxp3+ Treg cells. accompanied by antigen immunization reported induce antigen-specific transferable However, UVB-induced cells exerting suppression not well investigated yet. The effects were studied in murine models OVA-induced inflammat...