Human promyelocytic leukemia (HI-GO) cells were induced to differentiate into macrophage-like cells by treatment with i0 mol/L 1,25-dihydroxyvitamin D3 (VD3). A monoclonal antibody (MoAb, 60B8), reactive with the particulate of the differentiated cells but not of the untreated cells, was isolated. The antigen recognized by the MoAb became apparent two days after VD3 treatment. and its concentra...

The findings presented in this paper indicate that 60 gm. of liver tissue, taken from adult donor rabbits 2 weeks after injecting them with large amounts of bovine gamma-globulin, and transferred to the peritoneal cavities of recipient rabbits prepared for a secondary reaction, contain enough of the antigen to induce the formation of detectable amounts of precipitin in the recipient rabbits. On...

Gamma-Interferon (IFN-gamma) is a lymphokine produced by T lymphocytes. We find that recombinant human IFN-gamma induces expression of HLA-D antigens on human promyelocytic leukemia cells (HL-60) and enhances expression of HLA-D antigens on normal human monocytes and macrophages. Induction of both HLA-D antigen expression and HLA-D mRNA accumulation occurs within 1 day of exposure of HL-60 to I...

Background Lichen planus is classified as a common and chronic papulo – squamous disease. It has been associated with liver disease particularly hepatitis C virus (HCV) infection, in several studies. This study aimed to evaluate the controversial relationship between HCV infection and lichen planus. Patients and methods This was an analytical case-control study. The study included 60 patients w...

Fine-needle aspiration biopsy is a minimally invasive technique for obtaining sample material suitable not only for cytological grading but also for flow cytometry and for biochemical analyses. The prognostic value of tissue prostate-specific antigen (T-PSA) from fine-needle aspiration biopsies was compared with serum total and free prostate-specific antigen, the ratio of free:total serum prost...