Benzo[/]-3-[(p-chlorophenylamino)(hydrazino)methyl]-4-hydroxy-1,2-dihydro-2-quinolone was prepared by the addition of H Br on — CH=N bond of the Schiff base followed by condensation with hydrazine and was used in the synthesis of different substituted triazolines borne on a quinolone moiety giving rise to a system of high probability to be of great biological importance. Some other derivatives ...

Nanomaterials are increasingly used to the targeting of gram-positive and gram-negative bacteria as an alternative to antibiotics. Bacterial infections are a major cause of chronic infections and mortality. People requirement for new materials for pathogenic bacteria treatment. It seems that nanomaterial-based strategies can be resolving this problem. In this research, improved antibacterial na...

The purpose of this study was to determine the prevalence and molecular characterization of plasmid-mediated quinolone resistance (PMQR) genes (qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA) among ESBL-producing Klebsiella pneumoniae isolates in Kashan, Iran. A total of 185 K. pneumoniae isolates were tested for quinolone resistance and ESBL-producing using the disk diffusion method and double disk...

An outbreak of Enterobacter cloacae infections with variable susceptibility to fluoroquinolones occurred in the University Medical Center Utrecht in the Netherlands in 2002. Our investigation showed that a qnrA1 gene was present in 78 (94%) of 83 outbreak isolates and that a qnrA1-encoding plasmid transferred to other strains of the same species and other species. The earliest isolate carrying ...

As the living standard improves, disposable sanitary and household paper requires not only softness or easy to fluff in a dry state, but also good antibacterial property. In this study, series of alkyl quaternary ammonium salts (AQAS), kinds antibacterial-debonding agents, were synthesized by using two-step process. The SN2 nucleophilic substitution reaction was designed between triethanolamine...

We report on a procedure for the preparation, printing and curing of antibacterial poly(N-isopropylacrylamide) nanocellulose-reinforced hydrogels. These composites present highly anisotropic microstructure which allows to control modulate resulting mechanical properties. The incorporation such nanoparticles enables us modify both strength humidity-dependent swelling direction printed parts, off...

In the current study, fungi from mangrove ecosystem of Mumbai were isolated and their metabolites screened for antibacterial potential. Two weeks old broth mycelium extracted using chloroform methanol. Antibacterial property solvent extracts was evaluated at various concentrations (2 – 10 µg/ml) against Staphylococcus aureus, Bacillus subtilis, Enterococcus faecium, faecalis, Klebsiella pneumon...

in this study, microball nanosilver was produced with dimensions of about 1 micrometer in order to reduce the risks of absorption of nanosilver particles through skin and inhalation. different concentration levels of silver have been used in making of hand-sheets. the antibacterial properties of all hand-sheets were evaluated again escherichia coli and bacillus subtilis bacteria. results indica...

Quinolone resistance in clinical isolates of Campylobacter jejuni in Sweden increased more than 20-fold at the beginning of the 1990s. Resistance to 125 microgram of ciprofloxacin per ml in clinical isolates was associated with chromosomal mutations in C. jejuni leading to a Thr-86-Ile substitution in the gyrA product and a Arg-139-Gln substitution in the parC product.

In light of the eco-friendliness and antimicrobial property mangosteen pericarp (MP), this research investigates antibacterial activity biodegradable poly(lactic acid) (PLA)/poly(butylene succinate) (PBS) nonwoven fabric coated with MP extract. experiment, extract concentrations were varied between 0 (uncoated), 0.3, 0.5, 1, 3, 5 wt%, experimental bacteria strains Escherichia coli Staphylococcu...