conclusions the results of this study suggest that e. hebecarpa extracts can be used to inhibit the planktonic and biofilm forms of these selected bacteria. objectives in an effort to combat these industrial and medical bacterial biofilm problems, our study aims to determine the antimicrobial effect of euphorbia hebecarpa. materials and methods the inhibition efficiency of alcoholic extracts on...

background hospital patients who are nasal carriers of methicillin-resistant staphylococcus aureus (mrsa) are a high-risk potential threat to themselves and other hospitalized patients. the high antibiotic resistance of these isolates renders the treatment of related infections difficult. objectives the present study, for the first time investigated the prevalence of mrsa isolates in nasal carr...

conclusions vancomycin, but not teicoplanin, can be considered an effective antibiotic of choice for controlling infections caused by mdr cons in gorgan, depending on the bacterial species. background coagulase-negative staphylococci (cons) are clinically important, especially in nosocomial and neonatal infections. the increasing emergence of glycopeptide-resistant cons has made these agents th...

there are increasing reports of emergence of multiple drug resistant (mdr) acinetobacter spp in the world; however there are a few reports in our country. 145 a. baumannii isolates from distinct wards and children's medical center (cmc) in tehran were studied in order to find the profile of antibiotic resistance among them. 40.6% (59/145) of a. baumannii isolates were identified as mdr. overall...

For years, people have been overusing antibacterial products, resulting in bacteria that are insusceptible to antibacterial products. This is due to misconceptions that surround antibacterial products. Studies have shown that many people aren’t aware of the dangers of antibacterial products, and expect a prescription of antibiotics upon doctor visits even in cases where antibiotics do not help....

In recent years, infections caused by multi-drug resistant (MDR) pathogens have become a serious problem, especially in the nosocomial setting. Th e World Health Organization (WHO) has identifi ed antimicrobial resistance as one of the three most important problems for human health. Some authors have summarized this pheno menon with the word ‘ESKAPE’, to include the most frequent MDR microorgan...

The antibiogram study of methicillin resistant Staphylococcus aureus isolates revealed 100% resistance to vancomycin, bacitracin, erythromycin, ciprofloxacin and nalidixic acid. Eight isolates (53.3%) showed resistance to co-trimoxazole and one isolate to rifampicin, which was the drug of choice. An effort was made to evaluate the antimethicillin resistant Staphylococcus aureus activity of silv...

UNLABELLED Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were simulated in the in vitro hollow-fiber infection model (HFIM) system to identify the l...

Antibiotics and antimicrobial chemotherapeutics exist in large numbers in today’s pharmaceutical market. Despite their use is becoming increasingly restricted. The reason behind such a rapid decline is largely attributed to the development of drug resistance among microorganisms. Such a phenomenon is coupled by the toxicity possessed by many antimicrobials. Multiple drug resistance among highly...

There is rapidly mounting evidence that intracellular proteases in bacteria are compelling targets for antibacterial drugs. Multiple reports suggest that the human pathogen Mycobacterium tuberculosis and other actinobacteria may be particularly sensitive to small molecules that perturb the activities of self-compartmentalized peptidases, which catalyze intracellular protein turnover as componen...