OBJECTIVE To investigate the suitability of citrus-press cakes, by-products of the juice industry as a source for the whitening agents for cosmetic industry. METHODS Ethylacetate extracts of citrus-press cakes (CCE) were examined for their anti-melanogenic potentials in terms of the inhibition of melanin production and mechanisim of melanogenesis by using Western Blot analysis with tyrosinese...

Camellia tenuifloria is an indigenous Camellia species used for the production of camellia oil in Taiwan. This study investigated for the first time the potential antioxidant, anti-tyrosinase and anti-inflammatory activities of oil production byproducts, specifically those of the fruit shell, seed shell, and seed pomace from C. tenuifloria. It was found that the crude ethanol extract of the see...

Mango leaves are known to possess many health benefits but the industry only focused on mango fruit production, resulting in abundant being underutilized. In this study, we managed transform into a new fermented drink, which has pleasant taste through bio-fermentation process. Different maturity levels of were selected; premature (light brown, LBML), intermediate mature green, LGML) and (green,...

In mammalian melanocytes, melanosome is a highly specialized organelle where melanin is synthesized. Melanin synthesis is controlled by tyrosinase, the vital enzyme in melanogenic pathway. The present investigation is based on an effect of purified mushroom tyrosinase of Agaricus bisporus on B16F10 melanocytes for the melanin production via blocking pigment cell machinery. Using B16F10 melanocy...

The melanosome is a highly specialized organelle where melanin is synthesized. Tyrosinase and tyrosinase-related protein-1 (Tyrp1) are major melanosomal membrane proteins and key enzymes for melanin synthesis in melanocytes. Inulavosin, a melanogenesis inhibitor isolated from Inula nervosa (Compositae), reduced the melanin content without affecting either the enzymatic activities or the transcr...

In the presence of tyrosinase, red blood cells are Ipsed. Lysis follows an enzyme-mediated reaction, with the amount of lysis being proportional to the tyrosinase concentration. Cyanide, which inhibits tyrosinase, prevents lysis of the red blood cells by tyrosinase. Heat-denatured tyrosinase has no effect on red blood cells. Tyrosinase also exhibits a pronounced effect on the permeability of is...

White-rot basidiomycetes are the only microorganisms with ability to produce both hydrolytic (cellulases and hemicellulases) oxidative (ligninolytic) enzymes for degrading cellulose/hemicellulose lignin. In addition, they biologically active natural products important application in cosmetic formulations, either as pure compounds or standardized extracts. present work, three wild strains of Bas...