Tuberculosis (TB) is one of the most common infectious diseases in developing countries including Nepal. Delay in diagnosis and treatment of tuberculosis results in poor prognosis of the disease. This study was conducted to estimate diagnostic cut off values of Adenosine Deaminase (ADA) in cerebrospinal fluid (CSF) and pleural fluid and to evaluate the sensitivity, specificity, positive and neg...

silicosis is considered to be among the occupational lung diseases and associated with sandblasting, mining, quarrying and tunneling. acute silicosis is usually progressive diseaseand despite treatment with corticosteroids it leads to cardio-respiratory failure and death. alveolar silicoproteinosis is one of it’s acute presentations due to exposure to silica dust and lungs filling with proteina...

Biotransformation processes have been successfully utilized to obtain products of pharmaceutical, chemical, food, and agricultural interest, which are difficult to obtain by classic chemical methods. The compound with antituberculous activity, 9-methoxy-tariacuripyrone (1), isolated from Aristolochia brevipes, was submitted to biotransformation with the yeast Saccharomyces cerevisiae under cult...

BACKGROUND Amongst the numerous causes of intestinal obstruction listed in the literature, sclerosing encapsulating peritonitis also called Abdominal Cocoon (AC) is one of the rarest entities. Its characteristic feature is a thick fibrotic membrane encasing varying lengths of the small and large gut in a cocoon. In India, there is an increasing incidence of tuberculosis, especially in the rural...

INTRODUCTION Skeletal tuberculosis involving the small bones is less common than pulmonary tuberculosis. Tuberculous dactylitis involves the short tubular bones of the hands and feet more commonly in children. The bones of the hands are the one's more frequently affected than bones of the feet, with the proximal phalanx of the index and middle fingers as the commonest sites for infection. Sprea...

Four cases of polyarthritis concomitant with active tuberculosis is reported. In three patients pulmonary tuberculosis was confirmed by identification of Mycobacterium tuberculosis in the sputum and bronchoalveolar lavage specimens, and in another one tuberculous lymphadenitis was confirmed by excisional biopsy. In all patients arthritis resolved by tuberculosis treatment and did not recur ...

BACKGROUND Pericardial constriction is a serious complication of tuberculous pericardial effusion that occurs in up to a quarter of patients despite anti-tuberculosis chemotherapy. The impact of human immunodeficiency virus (HIV) infection on the incidence of constrictive pericarditis following tuberculous pericardial effusion is unknown. METHODS AND RESULTS We conducted a prospective observa...

Tuberculosis manifesting at extrapulmonary sites is relatively rare. Isolated cases involving small bones of the foot are rarest We herein present case a 30-year-old Indian female who presented with pain and wound discharging sinus over her left foot. In absence constitutional symptoms tuberculosis, this was diagnosed as isolated tuberculous osteomyelitis fifth metatarsal phalanx help radiograp...

STUDY DESIGN A retrospective study. PURPOSE This is a study of the diagnosis and treatment of tuberculous spondylitis and pyogenic spondylitis in atypical cases. OVERVIEW OF LITERATURE There have been several reports about clinical, hematological, pathological and radiological findings to differentiate pyogenic & tuberculous spondylitis. METHODS We screened 55 patients diagnosed with tube...

BACKGROUND Due to a similarity between the features of lymphoma and the features of tuberculosis, lymphoma may go unrecognized and undiagnosed in patients with tuberculosis. CASE PRESENTATION A 33-year-old Thai man presented to our center with typical clinical manifestations of tuberculous lymphadenitis, with negative tests for both acid-fast bacilli and fungi, and negative polymerase chain r...