Isothiocyanates (ITCs) are naturally occurring molecules belonging to highly reactive organosulphur synthons, with the general structure R–N=C=S. The precursor molecule glucosinolate anions are hydrolyzed enzymatically (under the effect of myrosinase enzymes) or unenzymatically to produce nitriles or isothiocyanates depending upon conditions such as pH and temperature. Brassicaceae  Family is k...

The hot and semi-arid region is prone to meteorological droughts; the lack of rain frequently accompanied by temperatures, strong winds, low humidity, which has impact limiting nutrient uptake agricultural yields. To overcome this problem a field study conducted during June, 2020 kharif season at farmers field, Chinna Dudyala village, Muddanur, Kadapa district, Andhra Pradesh aimed determine ef...

The increase in solar radiation and temperature as a result of climate change variability has increased sunburn damage to fruits, which highly affects quality yield tropical subtropical fruit plants. Solar injuries because conditions with low relative humidity, fruits left uncovered by foliage, plantations at higher altitudes UV radiation. Three different types on are distinguished: photooxidat...

The edible fungus Phellinus baumii Pilat (Hymenochaetaceae) has been used in Korean traditional medicines for strengthening health and prolonging life. An extract of the fruiting bodies of P. baumii was subjected to bioassay-guided fractionation based on its anti-inflammatory effects in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. The resulting fractions were chemically investigated, lea...

Although non-steroidal anti-inflammatory drugs (NSAIDs) and opioid compounds are widely used in the releif of pain, they are not always useful due to their side effects. It seems necessary to search for newer analgesic compounds. Therefore, we decided to study the analgesic effects of this plant. For extraction, percolation method was used and different weights of dried extract were dissolved i...

Four new 1,2,3-triazole phthalimide derivatives with a potent anti-inflammatory activity have been synthesized in the good yields by the 1,3-dipolar cycloaddition reaction from N-(azido-alkyl)phthalimides and terminal alkynes. The anti-inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of Swiss white mice to produce inflammation. All t...

Background: Cancer has spread rapidly all over the world, and its been considered a big health problem by international organizations. Today, patients prefer to use medicinal plants treat infectious non-infectious diseases. Objectives: Considering that Scutellaria therapeutic properties, this study was conducted investigate anti-cancer anti-bacterial effects of biologically active compounds spe...

The effect of 24 anti-amoebic and other chemotherapeutic compounds on six strains of hartmannellid amoebae was studied by tissue culture, agar diffusion, and liquid axenic culture. Of the recognized anti-amoebic compounds only one inhibited growth of the amoebae, which were remarkable for their resistance. Two compounds, hydroxystilbamidine isethionate and 5-fluorocytosine, showed some amoebici...

an efficient synthesis of some novel coumarin derivatives via 1, 4- michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (csa) under solvent free conditions is described. the corresponding michael addition products were obtained in good to excellent yield. the synthesized compounds were screened for their antibacterial activity against e. coli, s. aureus and an...