Nociceptive pain is a sensational discomfort that usually associated with injury or illness found affecting the body either internally externally. Crossopteryx febrifuga one of medicinal plants which are locally used in management especially North Central Region Nigeria. Many conventional drugs being applied managing aside not affordable and readily accessible by majority people at rural areas ...

background & aim: eugenia caryophyllata well known as clove is a tree from myrtaceae family that several parts of this plant traditionally used in dental care as an analgesic. this study aimed to assess the chemical composition, anti-inflammatory and anti-nociceptive activities of the essential oil extracted from clove buds. experimental: the essential oil of clove buds (eoc) was extracted ...

Background and objectives: Alternative medicine is widely used to replace a variety of commonly prescribed synthetic drugs in order to achieve a state of substantial efficacy with considerably less adverse effects. The present work has focused on the comparative evaluation of the analgesic efficacy of five members of Lamiaceae family to prioritize their potentials to be used he...

Background: Tolerance and dependence to anti-nociceptive effect of morphine restricted its use. Nowadays co-administration of morphine and other drugs suggests diminishing this tolerance. Baclofen is one of the drugs that may be beneficial in the attenuation of tolerance to morphine. Studies have shown that changes in transient receptor potential vanilloid type 1 (TRPV-1) expression during admi...