Abstract This study aims to determine the most frequent titers of anti-A and anti-B (both presumed immunoglobulin [Ig]M IgG) in Iranian group O blood donors compare these titer values with those found other studies. In addition, alloantibody production plasma levels four IgG subclasses were compared between high-titer non–high-titer groups. investigated 358 samples. Based on results, two groups...

SIR-The recent paper by Glatt and Anand [1] provides an excellent, comprehensive review of the natural history and treatment options with regard to HIV-related thrombocytopenia. We wish to discuss the efficacy of therapy with intravenous anti-rhesus D (Rho[D]) immunoglobulin in this setting. Glatt and Anand state that the drawbacks to intravenous anti-RHo(D) include lack of experience with its ...

within 1–20 h after anti-D infusion [3], supporting the concept of cytokine immunomodulation with anti-D therapy. A recent paper by Del Vecchio et al. [4] showed that IL-10 levels at the onset may predict the course of patients with ITP, and higher levels have a positive outcome on disease remission within 1 year, while high thrombopoietin levels were not helpful in predicting the course of dis...

The effects of actinomycin D were studied on successive stages of the primary and secondary (anamnestic) anti-Forssman immunoglobulin hemolysin responses induced in rabbits by the antigen, sheep red blood cells. (Fully developed anamnestic reactivity was tested 1.5-2 months after the start of an untreated initial response.) The stages of both responses include induction by antigen, the latent p...

1. Angelini A, Dragani A, Berardi A, Iacone A, Fioritoni G, Tortolano G. Evaluation of four different methods for platelet freezing. In vitro and in vivo studies. Vox Sang 1992; 62:146-51. 2. Currie LM, Livesey SA, Harper JR, Connor J. Cryopreservation of single-donor platelets with a reduced dimethyl sulfoxide concentration by addition of second-messenger effectors: enhanced retention of in vi...

OBJECTIVE The aim of this study is to evaluate the clinical and prognostic values of persistence of anti-hepatitis B core immunoglobulin M antibody in asymptomatic adults chronic hepatitis B surface antigen anti-hepatitis Be carriers and its absence in others. METHODS Fifty-two hepatitis B surface antigen/anti-hepatitis Be carriers with and 32 without anti-hepatitis B core immunoglobulin M ma...

Monoclonal anti-nuclear antibodies which are complexed to nucleosomes are able to bind to the glomerular basement membrane (GBM) in vivo, whereas purified antibodies do not bind. The positively charged histone moieties in the nucleosome are-responsible for the binding to anionic determinants in the GBM. We tested the hypothesis that the specificity of the autoantibodies complexed to the nucleos...

BACKGROUND FMH quantification is necessary to calculate an individual dose of prophylactic anti-RhD immunoglobulin and to diagnose fetal anaemia causes. We encountered a healthy woman with a numerous RBCs containing fetal haemoglobin (HbF). AIMS To investigate the cause of this sign and the correct evaluation of fetal RBCs in maternal circulation. MATERIALS AND METHODS Patients samples and ...

to study the humoral immune response to entamoeba histolytica infection, sera prepared from different cases of amoebiasis from gastroenterology ward of b.h.u hospital, including15 cases with amoebic liver abscess (ala), 10 cases with acute amoebic dysentery (ad) and 10 controls were examined by enzyme linked immuno sorbent assay (elisa), using crude amoebic antigen prepared from entamoeba histo...