A patient with typical Landry-Guillain-Barré-Strohl syndrome (LG-BS) developed bilateral optic neuritis. Laboratory studies showed hypersensitivity to both central and peripheral nervous tissue myelin. The occurrence of optic neuritis is presumably due to autohypersensitivity to central nervous tissue myelin. The initial lesions of the LG-BS syndrome in the peripheral nerves might have liberate...

Background: Horton’s disease (HD) or giant cell arteritis (GCA) is a segmental and plurifocal inflammatory panarteritis, predominant in large medium sized vessels. Ocular damage during frequent considered the most serious damage, possibly causing blindness 15% of cases recent series (1). Objectives: Describe different ophthalmological manifestations GCA. Methods: This retrospective monocentric ...

Three cases of chiasmal optic neuritis are described with bitemporal visual field loss and enlargement of the optic chiasm as demonstrated by computed tomography (CT). Exploratory craniotomies were performed in two of the patients, but no tumor was found. After corticosteroid treatment, all three patients experienced virtually complete restoration of normal vision. Although the CT presentation ...

We present a healthy male subject who developed progressive visual loss in the left eye initially diagnosed as optic neuritis. Upon suspicion of infectious etiology, testing was positive for tuberculosis. There were no signs or symptoms of active systemic tuberculosis infection. The patient responded swiftly to antimycobacterial therapy with return of vision and resolution of disc swelling. Pos...

Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and inflammatory nervous system disease. It leads to the loss of myelin in the white matter of brain, spinal cord and optic nerves. As a chronic disease with sudden and unpredictable Side effects and complications of the disease will lead to disability and dependency in life. Causes neurologic symptoms and sig. The purpose of the p...

Case Report: A 24 year-old female was admitted due to a sudden painful hypovision in the left eye. The etiological investigation was negative but brain MRI showed T2 hyperintensity of the left optic nerve with gadolinium enhancement, but no signal changes in the brain parenchyma. Eleven years before, she had been diagnosed with autoimmune thyroiditis based on hypothyroid goiter with biopsy-prov...

Optic neuritis is a common condition that causes reversible loss of vision. It can be clinically isolated or can arise as one of the manifestations of multiple sclerosis. Occasional cases are due to other causes, and in these instances management can differ radically. The treatment of optic neuritis has been investigated in several trials, the results of which have shown that corticosteroids sp...

PURPOSE To examine the occipital-lobe activation of patients with optic neuritis using near-infrared spectroscopy. DESIGN Experimental study. METHODS NIRS was performed on five patients with acute unilateral optic neuritis during monocular visual stimulation. As controls, six normal subjects were also tested in the same manner. RESULTS In the patients with optic neuritis, the changes in t...

Thirty patients with clinically uncomplicated optic neuritis were subjected to a battery of electrophysiological tests, including visual evoked response (VER), auditory brainstem evoked response (ABER) and somatosensory evoked response (SSER). Blink reflex, electronystagmography (ENG), and computed tomography examinations were also carried out on all patients. These non-invasive tests indicated...

OBJECTIVE To monitor the difference in conversion rates to multiple sclerosis (MS) in 46 patients with optic neuritis between patients with multifocal visual evoked potential latency delay and those with normal latency. DESIGN Prospective case series. SETTING Metropolitan neuro-ophthalmology clinic. PARTICIPANTS Forty-six patients with optic neuritis who did not have a diagnosis of MS on ...