BACKGROUND Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. METHODS One hundred-sixty three AS patients were included in a cross-se...

© 2013 The Authors. doi: 10.2340/16501977-1078 Journal Compilation © 2013 Foundation of Rehabilitation Information. ISSN 1650-1977 Objective: To evaluate the mean overall effects over a 1-year period of a multidisciplinary in-patient rehabilitation programme for patients with ankylosing spondylitis. Design: Observer-blinded, randomized controlled trial, with assessments made after 4 and 12 mont...

BACKGROUND/AIM To compare the differences in clinical characteristics and disease impact on life between patients with juvenile-onset ankylosing spondylitis (JoAS) and patients with adult-onset AS (AoAS). MATERIALS AND METHODS Demographic and clinical data were collected from 139 AS patients. Disease activity was defined with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Fu...

The HL-A antigen W.27 has been found in 88 to 96% of patients with ankylosing spondylitis (Brewerton, Caffrey, Hart, James, Nicholls, and Sturrock, 1973a; Caffrey and James, 1973; Schlosstein, Terasaki, Bluestone, and Pearson, 1973). More recently a high frequency of W.27 has been reported in Reiter's syndrome (Brewerton, Caffrey, Nicholls, Walters, Oates, and James, 1973c), acute anterior uvei...

OBJECTIVE To assess vascular endothelial growth factor (VEGF) correlations with new bone formation and bone marrow edema in patients with ankylosing spondylitis (AS) treated with golimumab (GOL). METHODS Following placebo control (through weeks 16 and 24), GO-RAISE (A Multicenter Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-TNF-α Monoclonal Antibody, Adm...

Aim. Increased cardiovascular morbidity and mortality have been observed in ankylosing spondylitis because of accelerated atherosclerosis. We measured carotid intima media thickness (CIMT) as a surrogate marker of atherosclerosis in this study. Methods. In this study 37 cases of AS and the same number of matched individuals were recruited. CIMT measurements were done using B-mode ultrasound. Di...

BACKGROUND Manipulative treatment for ankylosing spondylitis is a controversial subject, and no literature on using this therapy for advanced cases with fusion of the spine could be found. OBJECTIVE To discuss the case presentation of a patient with advanced ankylosing spondylitis who was treated with chiropractic manipulation and mobilization. Clinical features The patient was a 30-year-old ...

Much has been written on ankylosing spondylitis but nothing regarding its hindrance to pregnancy or its interference with normal labour. Since this disease is one involving pelvic joints, and since, as the disease progresses, ankylosis of the joints occurs, it is possible that ankylosing spondylitis would be a hindrance in pregnancy and in normal labour. Polley and Slocumb's (1947) short but co...

BACKGROUND Individuals with ankylosing spondylitis are at an increased risk of vertebral fractures. These are often unstable, leading to primary and secondary neurological injury and conferring high levels of morbidity and mortality. Fractures in these patients can occur after minimal trauma and are easily missed, with potentially disastrous consequences. OBJECTIVES To educate health professi...