In the present paper, electrochemical methods were used to investigate the behavior of ascorbic acid at a carbon paste electrode modified with 2,2'-((1E)-(1,2 phenylenebis(azanylylidene)) bis(methanylylidene))bis(benzene-1,4-diol) (PBD) and oxidized multiwall carbon nanotubes. The modified carbon paste electrode showed high electrocatalytic activity toward ascorbic acid; the current was enhance...

It is well-established that molecules which transport cations across cell membranes (cationophores) can have potent biological effects. Anion flux is also important to the cell and, correspondingly, anion carriers may be capable of biological activity. Indeed, chloride transporters have direct medical potential as treatments for cystic fibrosis and other diseases caused by defective channel pro...

A cationic surfactant-selective electrode for sensitive analysis of cationic surfactant has been developed by using a plasticized poly (vinyl chloride) membrane based on nanocomposite cation exchanger polypyrrole zirconium titanium phosphate. The electrode is excellently selective for the cetyl trimethyl ammonium bromide (CTAB) ion over inorganic ions and other cationic surfactants. The membran...

A sensitive electrochemical sensor was fabricated for selective detection of nitric oxide (NO) based on electrochemically reduced graphene (ErGO)-polyaniline (PANI)-gold nanoparticles (AuNPs) nanocomposite. It was coated on a gold (Au) electrode through stepwise electrodeposition to form AuNPs-PANI-ErGO/Au electrode. The AuNPs-PANI-rGO nanocomposite was characterized by Field Emission Scanning ...

A new plastic membrane ion-selective electrode for determination of metformin hydrochloride has been prepared, after forming the ion pair of metformin hydrochloride with sodium tetraphenylborate. Dioctyl phthalate and sodium tetraphenylborate were used as plasticizer and counter ion respectively. The electrode exhibited a linear potential response in the concentration range 1 × 10 M–1 × 10 M wi...

A new [2]rotaxane host system containing nitro-isophthalamide macrocycle and polyether functionalised pyridinium axle components is prepared via clipping and stoppering synthetic methodologies using chloride anion templation. After removing the chloride anion template, (1)H NMR titration experiments reveal the unique interlocked host cavity to be highly selective for binding chloride and bromid...

Ferricyanide anion has usually been used as a marker of ion-channel sensors. In this work we first found that ferricyanide, itself, can act as a stimulus to regulate the permeability of sBLM prepared from didodecyldimethylammonium bromide (a kind of synthetic lipid) on a GC electrode. We used cyclic voltammetry and a.c. impedance to investigate this phenomenon. The interaction between sBLM and ...

Excitatory amino acid transporters (EAATs) are essential for terminating glutamatergic synaptic transmission. They are not only coupled glutamate/Na(+)/H(+)/K(+) transporters but also function as anion-selective channels. EAAT anion channels regulate neuronal excitability, and gain-of-function mutations in these proteins result in ataxia and epilepsy. We have combined molecular dynamics simulat...