Among the multiple possibilities to study human pathologies, animal models remain one of the most used pathways. They allow to access to unavailable answers in human patients and to learn about mechanisms of action of drugs. Primarily developed with rats, animal models in anxiety have been adapted with a mixed success for mice, an easy-to-use mammal with better genetic possibilities than rats. ...

Activation of inflammatory gene expression by the transcription factor NF-kB is a central pathway in many inflammatory disorders, including colitis. Increased NF-kB activity has been linked with development of colitis in humans and animal models, thus it was unexpected when NF-kB-deficient mice developed spontaneous typhlocolitis. To further characterize this finding, we induced typhlocolitis i...

In ritual practice, which is the part of celebration annual holidays, Serbs usually choose different types animals. Thus, a pig most often sacrificed on Christmas, St. George?s Day - lamb, Elijah rooster, Mrata chicken, etc. The slaughter certain animal, carried out by wider community day year, in Bulgarian-Macedonian-Serbian area known as kurban. paper discusses animal species are particular h...

Abstract This systematic review aimed to assess the current knowledge of human–animal interactions (HAIs) in disaster settings and identify areas for future research. A Preferred Reporting Items Systematic Reviews Meta-Analyses search was conducted on three multidisciplinary databases, identifying English-language journal articles published between January 2000 February 2022 that explored benef...

We posit a new geometric perspective to define, detect, and classify inherent patterns of collective behaviour across a variety of animal species. We show that machine learning techniques, and specifically the isometric mapping algorithm, allow the identification and interpretation of different types of collective behaviour in five social animal species. These results offer a first glimpse at t...

489 Vol. 7, No. 3, May–June 2001 Emerging Infectious Diseases of serious gram-positive infections in humans (with no animal use counterparts) are in the pharmaceutical pipeline (e.g., LY333328 and daptomycin) or have recently been approved (e.g., linezolid). We hope that a fair balance can be achieved by the human medical and the animal health and production communities with regard to the types...

Animal viruses, some of which are probably unable to replicate in human cells, could be transmitted to people where they may be linked to tumours currently not attributed to viruses. Several human virus types have oncogenic potential in animals. A potential risk for acquiring such infections by handling and preparation of animal products was analysed against the background of available epidemio...

Editor’s key points † Animal models of diabetes show reduced onset and increased duration of peripheral nerve blocks. † This study aimed to evaluate the difference in block properties between diabetic and non-diabetic patients. † Using careful evaluation of sensory dysfunction, diabetic patients were found to have a prolonged duration of a sciatic nerve block. † Further study of the mechanisms ...

background: in modern life, the incidence of traumatic injuries increases daily. in accidents which lead to trauma, massive bleeding is the main cause of death. nowadays, many different chemical and herbal agents are available for quick control of bleeding. objectives: in this study, we compare the effectiveness of two different types of chemical agents for control of bleeding in an animal mode...

results our data showed that the eae induction in group one was significantly more successful than group two (with the mean score > 3). conclusions although the eae is still a scientific method to induce ms in rodents, it requires more attention to environmental factors that might influence the result. the mechanisms of these factors are unknown, but it seems that the role of housing environmen...