نتایج جستجو برای: animal imaging
تعداد نتایج: 654685 فیلتر نتایج به سال:
Background: Oxytocin (OT) is a paracrine hormone with various biological activities and many sex organs in both sexes, as well as many tumor cells have shown to have related receptors. In this study the development of a receptor imaging tracer for possible tumor imaging has been described. Materials and Methods: OT was successively labeled with [67Ga]-gallium chloride after conjugation with fre...
PURPOSE Animal models of breast cancer metastases that recapitulate the pattern of metastatic progression seen in patients are lacking; metastatic breast cancer models do not currently exist for evaluation of immune-mediated therapies. We have developed and characterized a preclinical model for the evaluation of immune-mediated metastatic breast cancer therapies. EXPERIMENTAL DESIGN The NT2.5...
Initially using clinical-scale instrumentation, imaging provided a non-invasive means of assaying biological structure and function in vivo. The development of dedicated small animal imaging systems followed and, more recently, techniques in molecular imaging have been established to allow imaging modalities to be combined into multi-modal methods. Among these, the combination of positron emiss...
In vivo magnetic resonance (Mr) imaging and spectroscopy are expanding our capability to observe and investigate many biomedical processes without invasive interventions. The unique 900-Mhz ultra-wide bore (uWB) 21.1 tesla magnet built at the Magnet lab in Tallahassee provides unprecedented opportunities to examine living systems. in this report, we present our first experiences and the results...
OBJECTIVE A thyroid rat model combining functional and anatomical information would be of great benefit for better modeling of thyroid physiology and for absorbed dose calculations. Our aim was to show that (124)I-PET and CT small animal imaging are useful as a combined model for studying thyroid physiology and dose calculation. METHODS Seven rats were subjects for multiple thyroid (124)I-ima...
magnetic resonance imaging (mri) is a notable medical imaging technique that makes of phenomenon of nuclear magnetic resonance. because of the resolution and the technology being harmless, mri has considered as the most desirable imaging technique in clinical applications. the visual quality of mri plays an important role in accuracy of medical delineations that can be seriously degraded by exi...
در حال حاضر چندین روش برای اندازه گیری چربی زیرپوستی بدن در حوزه های بالینی وجود دارد ، مانند : magnetic resonance imaging(mri)، (computer tomography(ct، ultrasound imaging(us) ، dual energy x-ray absorptiometry(dexa). این روش ها بطور وسیعی در حوزه های بالینی به عنوان وسایل دقیق و مفید ، مورد استفاده قرار می گیرند. به هر حال این روش ها محدودیت های زیادی مانند هزینه بالا و یا خطر تابش اشعه را دا...
The use of structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI) in animal models of neuropathology is of increasing interest to the neuroscience community. In this work, we present our approach to create optimal translational studies that include both animal and human neuroimaging data within the frameworks of a study of post-natal neuro-development in intra-uterine c...
Among the several imaging technologies applied to in vivo studies of research animals, positron emission tomography (PET) is a nuclear imaging technique that permits the spatial and temporal distribution of compounds labeled with a positron-emitting radionuclide to be determined noninvasively. It can be viewed as an in vivo analog of classic autoradiographic methods. Many different positron-lab...
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