BACKGROUND Data on prevalence of glaucoma in East Asia are scarce. OBJECTIVE To determine the prevalence and clinical characteristics of glaucoma in adult Chinese Singaporeans. METHODS A group of 2000 Chinese people, aged 40 to 79 years, were selected from the electoral register of Tanjong Pagar district in Singapore using a disproportionate, stratified, clustered, random-sampling procedure...

Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clini...

BACKGROUND Glaucoma is the leading cause of irreversible blindness. Although primary open-angle glaucoma is more common, primary angle-closure glaucoma (PACG) is more likely to result in irreversible blindness. By 2020, 5·3 million people worldwide will be blind because of PACG. The current standard care for PACG is a stepped approach of a combination of laser iridotomy surgery (to open the dra...

BACKGROUND A case is reported of acute bilateral myopia and angle closure glaucoma in a 7-year-old patient from topiramate toxicity. This is the second known reported case of topiramate induced acute angle closure glaucoma and third known reported case of topiramate induced acute myopia in a pediatric patient. CASE PRESENTATION This case presents a 7-year-old who had recently begun topiramate...

A small series of patients who underwent iridocycloretraction between 1969 and 1976 is analysed. All patients had previously undergone peripheral iridectomy for primary angle-closure glaucoma, and all had 360 degrees of peripheral anterior synechiae, as seen with the gonioscope. It was found that iridocycloretraction was successful in an unacceptably low percentage of cases, and its success was...

The IOP was controlled in 40 eyes (31 cases) of primary angle-closure glaucoma with Nd:YAG laser iridotomy. On follow-ups in 3 years, the differences in IOP, visual acuity, and the peripheral chamber depth from the preoperative values were very significant. The iridotomy hole closed spontaneously in 4 eyes. The success rates were 94% and 91% at 6 months and 2 years postoperative respectively, w...

Noninvasive medical imaging techniques have high potential in the field of ocular imaging research. Angle closure glaucoma is a major disease causing blindness and a possible way of detection is the examination of the anterior chamber angle in eyes. Here, a simple optical method for the evaluation of angle-closure glaucoma is proposed and illustrated. The light propagation from the region assoc...

Background: Chronic angle-closure glaucoma (CACG) is a visually destructive disease. Effective management of CACG requires identifying eyes with narrow angle.
 Objective: To compare pentacam gonioscopy in detecting angles CACG.
 Method: We enrolled 101 glaucoma. Gonioscopy was performed on all eyes. Using Shaffer’s grading, subjects were classified into angle closure and open angle. A...

Small-angle X-ray scattering (SAXS) is an established technique that provides low-resolution structural information on macromolecular solutions. Recent decades have witnessed significant progress in both experimental facilities and in novel data-analysis approaches, making SAXS a mainstream method for structural biology. The technique is routinely applied to directly reconstruct low-resolution ...