THE ophthalmoscopic appearances of hereditary degenerative macular lesions vary greatly, as do the functional disturbances produced, the time of onset, the course, and the mode of inheritance. Behr (1920), finding the time of onset fairly constant in the members of one sibship, classified hereditary macular degeneration on this basis, starting with the congenital cases (Best, 1905), proceeding ...

We study near-wall streaks that form herringbonelike patterns in Taylor-Couette turbulence and in counter-rotating Taylor-Couette turbulence through three-dimensional direct numerical simulations. The orientation, axial distribution, onset, and tilting angle of these streaks are characterized.

Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly. AMD patients have elevated levels of membrane attack complex (MAC) in their choroidal blood vessels and retinal pigment epithelium (RPE). MAC forms pores in cell membranes. Low levels of MAC result in an elevation of cytokine release such as vascular endothelial growth factor (VEGF) that promotes the...

THE ophthalmoscopic appearances of hereditary degenerative macular lesions vary greatly, as do the functional disturbances produced, the time of onset, the course, and the mode of inheritance. Behr (1920), finding the time of onset fairly constant in the members of one sibship, classified hereditary macular degeneration on this basis, starting with the congenital cases (Best, 1905), proceeding ...

PURPOSE To report the effect of intravitreal anti-vascular endothelial growth factor injections (IVI) on visual acuity in eyes with choroidal neovascularisation (CNVM) and co-existent vitreomacular traction (VMT) or when VMT has developed during the course of treatment. METHODS Retrospective interventional case series of seven eyes in seven patients. VMT was monitored with serial optical cohe...

OBJECTIVE The correlation between the extent of fatty streaks, more advanced atherosclerotic lesions, and community rates of coronary artery disease (CAD) is substantially higher for the coronary artery compared to the aorta. We sought to determine whether a genetic basis contributes to these differences. APPROACH AND RESULTS We conducted a cluster analysis of 6 subclinical atherosclerosis ph...

This paper studies the problem of prominent streak discovery in sequence data. Given a sequence of values, a prominent streak is a long consecutive subsequence consisting of only large (small) values, e.g., consecutive games of outstanding performance in sports, consecutive hours of heavy network traffic, consecutive days of frequent mentioning of a person in social media, and so on. Prominent ...

We present a relatively simple, deterministic, theoretical model for the sublayer streaks in a turbulent boundary layer based on an analogy with Klebanoff modes. Our approach is to generate the streamwise vortices found in the buffer layer by means of a vorticity source in the form of a fictitious body force. It is found that the strongest streaks correspond to a spanwise wavelength that lies w...