Local anesthetics are the safest drugs used in dentistry for pain management, but cause undesirable qualities such as stinging and burning upon injection, relatively slow onset of action, and unreliable or no anesthesia when injected into infected tissues. Buffering of local anesthetics has been demonstrated to counteract these undesirable qualities of local anesthetics. Recent advances in tech...

To the Editor:—Caudal anesthesia with ropivacaine as an adjunct to general anesthesia recently has been shown to provide duration of pain relief and sensory and motor effects similar to bupivacaine. We report the time course of the blockade after caudal epidural injection of ropivacaine in a 1,090-g awake, preterm infant. A 26-day-old, 1,090-g male infant was scheduled for partial amputation of...

Purpose: Some anesthetic drugs are known to have influence on circulation due hemorheological effects.We aimed investigate the possible effects of ketamin-xylazine anesthesia, which is extensively used inexperimental animal laboratories parameters.Materials and methods: Adult, male Wistar-Albino rats were divided into two as control (pre-anesthesia)and post-anesthesia (n=17). Ketamin-HCl/Xylazi...

tranexamic acid is generally used in the treatment of disorders that predispose one to bleeding. it is a synthetic lysine analog that has strong antifibrinolytic activity. plasminogen binds to fibrin to form plasmin, which in turn degrades fibrin into fibrin degradation products. tranexamic acid blocks the lysine binding site on plasminogen and prevents interaction with fibrin. tranexamic acid ...

introduction: incomplete anesthesia of inflamed teeth is a well known clinical occurrence and the purpose of this study was to evaluate the effectiveness of ibuprofen as a premedication in improving the quality of anesthesia in patients with inflamed teeth pulps. methods: forty patients with the diagnosis of irreversible pulpitis in one mandibular tooth were selected. two other teeth in the sam...

conclusions although almost all of the < 1 year-old children could be sedated with midazolam alone, most of the > 1 year-old children required ketamine or general anesthesia. performing circumcision when children are less than 1 year old decreases the risk of complications due to anesthesia and lowers the costs compared with performing the procedure on older children. results a total of 603 chi...

background in clinical practice, the level of sensory block in spinal anesthesia in opium abusers is lower than that in non-abusers because of adaptive changes caused by opium use. objectives the aim of this study was to investigate the level of sensory block resulting from the intrathecal administration of 0.5% bupivacaine in opium abuser patients undergoing lower extremity and lower abdominal...

background spinal anesthesia is a common procedure in the anesthesia. in some studies it has been shown that chronic use of opioids is associated with shorter duration of spinal anesthesia when local anesthetics are applied. objectives this trial was conducted in order to determine effect of fentanyl on the duration of spinal block by bupivacaine in chronic opium abusers who undergo spinal anes...