The hemagglutinin protein (HA) of the influenza virus family is a major antigen for protective immunity. Thus, it is a relevant target for developing vaccines. Here, we describe a human CD4(+) T cell epitope in the influenza virus HA that lies in the fusion peptide of the HA. This epitope is well conserved in all 16 subtypes of the HA protein of influenza A virus and the HA protein of influenza...

in order to study the effect of different levels of the manure and foliar application of zn and mn fertilizers on the quantitative and qualitative yield of soybeans (var. williams), a factorial experiment was conducted in a randomized complete block design with three replications in 2012. treatments involved three levels of fertilizer: manure (zero as control; six and 12 t/ha), two levels of mn...

Thyme (Thymus vulgaris L.) is an important medicinal plant with highly valuable essential oils. In this study, effects of different fertilizer treatments and cuts on Thymus vulgaris L. was evaluated in 2008-2009. The research was conducted at Alborz Research Station, Research Institute of Forests and Rangelands, Karaj, Iran. The Experimental design was split plot in time in the form of a random...

Trichoderma are ubiquitous soil fungi that include species widely used as biocontrol agents in agriculture. Many isolates are known to secrete several secondary metabolites with different biological activities towards plants and other microbes. Harzianic acid (HA) is a T. harzianum metabolite able to promote plant growth and strongly bind iron. In this work, we isolated from the culture filtrat...

Antigen-specific T helper cells present in peripheral blood at very low frequencies are capable of rapid clonal expansion during antigenic challenge. The exquisite specificity of this response provides for activation and expansion of a very select cohort of T cells, a feature we have used to directly identify and quantify human epitope-specific T helper cells from peripheral blood. Soluble tetr...

Bone marrow-derived APCs present both parenchymal-self and pathogen-derived Ags in a manner that elicits either T cell tolerization or immunity, respectively. To study the parameters that confer tolerogenic vs immunogenic APC function we used an adoptive transfer system in which naive TCR transgenic hemagglutinin (HA)-specific CD4(+) T cells are either tolerized upon encountering HA expressed c...

In this study, the effects of concentration and application time of ethephon on growth parameters; stem height, stem diameter, biomass, carbohydrate content; sucrose content, invert sugar, brix value, and juice volume of two sweet sorghum cultivars were determined. Three ethephon application time (8 leaves, booting, and flowering) and five ethephon concentrations (0, 200, 400, 600, and 800 ppm)...

The experiment was conducted under in vitro and field conditions to observe the effect of bio-agents, botanical and fungicides against Alternaria triticina. Eight treatments were taken up with three replications and data collected was analyzed using CRD. Maximum inhibition per cent mycelia growth was observed in Propiconazole (89.72%), Hexaconazole (88.44%), Vitavax (87.70%), followed by Tricho...