نتایج جستجو برای: ancient dna

تعداد نتایج: 542037  

Journal: :Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2015
Kirsten I Bos Günter Jäger Verena J Schuenemann Åshild J Vågene Maria A Spyrou Alexander Herbig Kay Nieselt Johannes Krause

DNA capture coupled with next generation sequencing is highly suitable for the study of ancient pathogens. Screening for pathogens can, however, be meticulous when assays are restricted to the enrichment of single organisms, which is common practice. Here, we report on an array-based DNA capture screening technique for the parallel detection of nearly 100 pathogens that could have potentially l...

2010
Michael Hofreiter

High-capacity sequencing technologies have dramatically reduced both the cost and time required to generate complete human genome sequences. Besides expanding our knowledge about existing diversity, the nature of these technologies makes it possible to extend knowledge in yet another dimension: time. Recently, the complete genome sequence of a 4,000-year-old human from the Saqqaq culture of Gre...

Journal: :Current Biology 2003
Hendrik Poinar Melanie Kuch Gregory McDonald Paul Martin Svante Pääbo

The determination of nuclear DNA sequences from ancient remains would open many novel opportunities such as the resolution of phylogenies, the sexing of hominid and animal remains, and the characterization of genes involved in phenotypic traits. However, to date, single-copy nuclear DNA sequences from fossils have been determined only from bones and teeth of woolly mammoths preserved in the per...

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