For well-designed confirmatory research, all analysis decisions that could affect the confirmatory results should be planned and registered prior to data collection. These decisions include: the specific statistical test for each confirmatory hypothesis, whether the test is one-sided or twosided, the criterion for acceptable evidence, any transformations or adjustments to the data, any criteria...

introduction: the diagnostic work-up of allergic rhinitis (ar) is first and foremost based on the combination of clinical history data and results of skin prick tests (spt). other tests, including specific ige measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization ...

Purpose. This study aims to evaluate the process of brain development in neonates using combined amide proton transfer (APT) imaging and conventional magnetization transfer (MT) imaging. Materials and Methods. Case data were reviewed for all patients hospitalized in our institution's neonatal ward. Patients underwent APT and MT imaging (a single protocol) immediately following the routine MR ex...

recently, specific attention has been paid to aptamers, short dna or rna, as a tool for cancer diagnosis and therapy. in the present study mcs nanogels were prepared by myristate: chitosan at 1:9 ratio and were characterized by several techniques. a selected ssdna aptamer(apt) capable of detecting lncap cells was linked to myristilated chitosan nanogels (apt-mcs) by glutaraldehyde and loaded wi...

UNLABELLED Phenotypic variation is prevalent in the zoonotic pathogen Campylobacter jejuni, the leading agent of enterocolitis in the developed world. Heterogeneity enhances the survival and adaptive malleability of bacterial populations because variable phenotypes may allow some cells to be protected against future stress. Exposure to hyperosmotic stress previously revealed prevalent differenc...

here‎, ‎we aim to develop a new algorithm for solving a multiobjective linear programming problem‎. ‎the algorithm is to obtain a solution which approximately meets the decision maker's preferences‎. ‎it is proved that the proposed algorithm always converges to a weak efficient solution and at times converges to an efficient solution‎. ‎numerical examples and a simulation study are used to...