The production of antimicrobial peptides (AMPs) represents an ancient form of host defence against microbial pathogens and has been identified in both plants and animals. Among the many different antimicrobial peptides, cathelicidins and defensins are the two major families that have been intensively studied in mammals. These small AMPs are usually hydrophobic and highly charged, which enables ...

A majority of terrestrial and marine organisms use to fend off a wide range of microorganisms, including bacteria and fungi by employing “antimicrobial peptides (AMPs)” that are ribosomally synthesized from proteinogenic amino acids. AMPs are a primary component of innate immune mechanisms in marine invertebrates. In contrast, marine sponges seem to contain no AMPs, but often contain nonribosom...

Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many organisms and are promising candidates to treat infections caused by pathogenic bacteria to animals and humans. AMPs also display anticancer activities because of their ability to inactivate a wide range of cancer cells. Cancer remains a cause of high morbidity and mortality worldwide. Therefore, the developme...

Frontal analysis continuous capillary electrophoresis (FACCE) was carried out for a series of random copolymers of an ionic monomer, sodium 2-(acrylamido)-2-methylpropanesulfonate (AMPS), and a nonionic monomer, acrylamide (AAM). The electropherograms appeared in order of anionic content and were generally sigmoidal, in contrast to that of hyaluronic acid (HA), which was abrupt and discontinuou...

Antimicrobial peptides (AMPs) are being intensively investigated as they considered promising alternatives to antibiotics where their clinical efficacy is dwindling due the emergence of antimicrobial resistance (AMR). Accompanying with development AMPs, a number fluorescent probes have been developed facilitate understanding modes action AMPs. These used monitor binding process, determine worki...

Environmental changes, failures, collisions or even terrorist attacks can cause serious malfunctions of the delivery systems. We have presented a novel approach improving resilience of Autonomous Moving Platforms AMPs. The approach is based on multi-level state diagrams describing environmental trigger specifications, movement actions and synchronization primitives. The upper level diagrams all...

Lab Assignments Instrumentation Labs: Name of Lab Assignment: Lab 1 Introductory Experiments and Linear Circuits I [1] Lab 2 Linear Circuits II [2] Lab 3 Semiconductor Diodes [3] Lab 4 JFET Circuits I [4] Lab 5 JFET Circuits II [5] Lab 6 Op Amps I [6] Lab 7 Op Amps II [7] Lab 8 Op Amps III [8] Lab 9 LabVIEW Programming [9] Lab 10 Analog to Digital and Digital to Analog Conversion [10] Lab 11 Si...

Antimicrobial peptides (AMPs) are evolutionarily ancient factors of the innate immune system that serve as a crucial first line of defense for humans, animals, and plants against infection. This review focuses on the structural organization, biosynthesis, and biological functions of AMPs that possess a β-hairpin spatial structure. Representatives of this class of AMPs are among the most active ...

Antimicrobial peptides (AMPs) are an ancient group of molecules that are expressed in many species ranging from bacteria to humans. At least 1200 naturally-occurring AMPs have been identified which display considerable diversity in their primary sequences, lengths, structures, and biological activities (Wang et al., 2009). Generally speaking, these peptides have been studied due to their abilit...

In the presence of specialized proteins or peptides, a biological membrane can spontaneously restructure itself to allow communication between the intracellular and the extracellular sides. Examples of these proteins include cell-penetrating peptides and antimicrobial peptides (AMPs), which interact with cell membranes in complex ways. We briefly review cell-penetrating peptides and AMPs, and d...