BACKGROUND AND PURPOSE As adenosine 5'-triphosphate (ATP) is one of the inhibitory mediators of the bladder outflow region, this study investigates the possible release of ATP or related purines in response to electrical field stimulation (EFS) and the purinoceptor(s) involved in nerve-mediated relaxations of the pig urinary bladder neck. EXPERIMENTAL APPROACH Urothelium-denuded and intact ph...

A field experiment was conducted on a sloping grassland soil in southwest England to investigate the downslope transport of nitrogen in soil water following the application of cattle manure, slurry and inorganic fertilizer. Transport of nitrogen (N) species was monitored on hydrologically isolated plots. Manure (50 t ha"), slurry (50 m ha") and fertilizer (250 kg N ha") were applied in February...

Functionalization of single-walled carbon nanotubes (SWNTs) with covalently grafted amine moieties provides reactive fillers with potential covalent anchoring to an epoxy matrix. Manufacturing and characterization of a high performance epoxy system reinforced with as-grown and aminated SWNTs are presented through four different approaches. Epoxy composite materials incorporating SWNTs aminated ...

Hiperurisemia atau asam urat merupakan produk akhir (eksresi) dalam tubuh dari metabolisme purin. Penelitian ini bertujuan untuk mengetahui aktivitas antihiperurisemia ekstrak etanol kulit petai menggunakan maserasi. Metode maserasi lebih efektif karena tidak pemanasan sehingga senyawa yang bersifat termolabil akan diambil terurai rusak. Kulit memiliki flavonoid dapat mengatasi antihiperurisemi...

The title compound, C17H19N5O2, features an almost planar purine skeleton (r.m.s. deviation = 0.009 Å) substituted by a tetra-hydro-furan ring, which adopts an envelope conformation. The purine and benzene rings subtend a dihedral angle of 66.70 (3)°. In the crystal, pairs of N-H⋯N hydrogen bonds connect adjacent mol-ecules into inversion dimers. C-H⋯N, C-H⋯O, C-H⋯π and π-π inter-actions [pyrim...

In the title compound, C(10)H(14)ClN(5), the imidazole and pyrimidine rings are essentially planar [maximum deviation = 0.0013 (14) and 0.0207 (13) Å, respectively]. In the crystal, the mol-ecules are linked by weak C-H⋯N inter-actions into chains parallel to the c axis and the crystal packing is stabilized by additional weak C-H⋯N and C-H⋯Cl inter-actions.

The title purine derivative, C7H7N5O3, is an adduct of guanine with glyoxal. In the mol-ecule, the di-hydro-imidazole ring adopts a twisted conformation on the C-C bond, and the two hydroxyl groups lie on opposite sides of the mean plane of the ring. In the crystal, the mol-ecules are linked by N-H⋯O, O-H⋯N and N-H⋯N hydrogen bonds forming a three-dimensional framework. The crystal packing is r...

A series of phenylenediamidinate rare earth metal complexes 1,4-C6H4[C(NR)2Ln(o-CH2C6H4NMe2)2]2 (R = 2,6-(i)Pr2-C6H3, Ln = Y (2a), Lu (2b), Sc (2c)) were synthesized by deprotonation of 1,4-C6H4[C(NR)(NHR)]2 (1) with two equivalents of n-BuLi followed by reacting with two equivalents of anhydrous LnCl3 and subsequently four equivalents of Li(o-CH2C6H4NMe2), or by protolysis of [Ln(o-CH2C6H4NMe2...