In an open non -comparative trial forty ambulant patients with chronic psoriasis vulgaris were treated with non -occlusive application of Sicorten® cream twice by day and Sicorten® ointment once at night for up to 30 days. This combined regimen yielded good (marked improvement) to very good (complete clearance) results in 92.5% of the patients treated. The onset of therapeutic effect was observ...

MUSCLE pains have been reported as occurring after the administration of suxamethonium chloride. Bourne et al. (1952) made passing mention of this, but not until 1954 did Churchill-Davidson fully describe these pains and determine their incidence — primarily in the ambulant patient. His series was small, covering 68 patients. In view of considerable speculation on the frequency and importance o...

Twelve patients (17 feet) with progressive neuromuscular planovalgus foot deformity underwent an extra-articular subtalar arthrodesis with the combined Batchelor-Grice procedure. All patients were ambulant and received conservative treatment with braces and special orthopaedic shoes before the operation. Postoperatively the feet were immobilized in short leg casts for 6 weeks. Evaluation was ba...

An investigation into the relations between the daily dose of digoxin, drug regimen, serum digoxin concentration, and creatinine and digoxin clearance was carried out in a group of elderly ambulant patients in domiciliary practice. Moderate to severe impairment of renal function was found both in patients taking digoxin and in elderly control subjects. Plasma digoxin levels were not related to ...

Serial measurements of bone mineral in 17 ambulant female patients with rheumatoid arthritis (RA) of recent onset and 19 age matched female controls were made in the radius by computed tomography and in the vertebrae by dual photon absorptiometry. Loss of trabecular bone from the distal radius was more rapid in RA (p = 0.0014), but there was no difference in the rate of loss of bone mineral fro...

The relative benefits and risks of reserpine and guanethidine were compared in patients with thiazide-treated mild to moderate hypertension (diastolic pressure 95-115 mm Hg). Fortynine ambulant patients (30 men, 19 women) were treated throughout the study with hydrochlorothiazide, 50 mg/day. In this double blind crossover study each drug was added in graded increments until a predetermined ther...

In this paper we report an investigation of venous pressures during exercise in ambulant patients. The investigation was undertaken because we wished to assess more accurately the abnormal venous mechanisms in patients complaining of swollen, painful or ulcerated legs. Phlebography, upon which great reliance has formerly been placed, has two limitations. Firstly, it yields only a knowledge of a...

During the continuous monitoring of intra-arterial blood pressure in ambulant hypertensive subjects, 18 episodes of coitus were recorded in 11 subjects. Peak values of up to 300/175 mmHg found, the mean for men being 237/138 mmHg and for women 216/127 mmHg. Two patients with coital symptoms (cephalgia and syncope) showed no unusual responses and, when restudied after beta-blockade, one subject ...

We studied the urinary excretion of organic acids by normal human subjects in an ambulant normal population, chosen without conscious bias. Quantitative ranges and frequency distribution patterns of excretion are reported, as a basis on which to compare results obtained for patients whose clinical condition suggests that their excretion values may be abnormal. The quantitative valuse we observe...

Supporting ambulant care through information technologies will assist the care personnel in their everyday routine resulting in more time for their patients. Therefore the MARIKA project focusses on developing an assistance system for facilitating the care documentation process through pervasive technologies. In this context, various data need to be handled which requires database techniques fo...