نتایج جستجو برای: ambrisentan

تعداد نتایج: 197  

2018
Anton Vonk-Noordegraaf Berend E. Westerhof

The function of the right ventricle (RV) determines the fate of patients with pulmonary hypertension (PH). This already became apparent from the first registry of patients with pulmonary arterial hypertension (PAH) showing that right ventricular parameters rather than (arterial) load parameters determine prognosis. In more recent years it has been recognized that load dependent right ventricula...

Journal: :Chest 2021

FOR RELATED ARTICLE, SEE PAGE 277Pulmonary arterial hypertension (PAH) remains a disease with significant morbidity and mortality despite plethora of modern medications known mechanisms action an active search for novel therapeutic targets approaches.1Galie N. Humbert M. Vachiery J.-L. et al.2015 ESC/ERS Guidelines the diagnosis treatment pulmonary hypertension. The Joint Task Force Diagnosis T...

Journal: :The European respiratory journal 2003
M Humbert O Sitbon G Simonneau

Pulmonary arterial hypertension (PAH) refers to a disease spectrum of the small pulmonary arteries leading to a progressive increase in pulmonary vascular resistance, right ventricular failure and, ultimately, death [1]. It is usually accepted that a vasoconstrictive factor is involved in PAH [2]. However, pure vasodilators, such as calcium channel blockers, have so far provided little or no be...

Journal: :Annals of the Rheumatic Diseases 2023

Background Pre-capillary pulmonary hypertension (precapPH) affects 9-15% of patients with systemic sclerosis (SSc) and may be associated interstitial lung disease (ILD) variable extent. Immunosuppressants (IMS) are standard care for treating ILD, skin or musculoskeletal manifestations in SSc. However, their beneficial effect on precapPH remains unclear. Objectives To determine whether exposure ...

Journal: :Chest 2021

FOR RELATED ARTICLE, SEE PAGE 781Pulmonary arterial hypertension (PAH) affects up to 10% of patients with systemic sclerosis (SSc) and is a leading cause morbidity mortality in this devastating disease.1Tyndall A.J. Bannert B. Vonk M. et al.Causes risk factors for death sclerosis: study from the EULAR Scleroderma Trials Research (EUSTAR) database.Ann Rheum Dis. 2010; 69: 1809-1815Crossref PubMe...

2015
Patricia E. Molina David M. Pollock Jane F. Reckelhoff Barbara T. Alexander John Chatham David Gutterman M. Harold Laughlin Lisa Leon Marshall H. Montrose Rudy M. Ortiz Irene C. Solomon Bill J. Yates Hannah V. Carey Martin Frank Meredith Hay Robert Hester Kevin C. Kregel Wolfgang Kuebler Curt Sigmund J. Michael Wyss Adviye Ergul Anil Gulati Ivana Vaneckova Masashi Yanagisawa Anthony Davenport Noriaki Emoto Matthias Barton Constantino Iadecola Janet Maguire Ariela Benigni John Pernow Anna Bagnato Marilena Loizidou David Webb Rita Tostes Donald Kohan Yasuo Matsumura Jennifer Pollock Jennifer Sullivan Martine Clozel Pedro D’Orleans-Juste

s of Invited and Contributed Presentations 1.0 Novel Aspects of the Endothelin System....................................................................13 2.0 The Immune System and Endothelin......................................................................13 3.0 Submitted Abstracts..........................................................................................13 4.0 ET, Sex and ...

Journal: :The Physiologist 2016
Maria Lourdes Alarcón Fortepiani

s of Invited and Contributed Presentations 1.0 Novel Aspects of the Endothelin System....................................................................13 2.0 The Immune System and Endothelin......................................................................13 3.0 Submitted Abstracts..........................................................................................13 4.0 ET, Sex and ...

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