Alzheimer Disease (AD) is a neurodegenerative disorder and the most common form of dementia. Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment, but includes strong interactions with immunological mechanisms in the brain. In vitro and animal studies have linked neuroinflammation to Alzheimer's disease (AD) pathology. Studies on marke...

1 Chertkow, H., Feldman, H. H., Jacova, C., & Massoud, F. (2013). Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: consensus from the Canadian conference on diagnosis of dementia. Alzheimers Research and Therapy, 5, S2. Notes: There have been several newly proposed sets of diagnostic criteria for Alzheimer's disease/mild cognitive impairme...

BACKGROUND Presenile dementia of alzheimer type is a rare condition, and a report drawn from a large population may be useful to general practitioners. AIM A study was undertaken in the Northern Regional Health Authority area to investigate general practitioner referral practice, hospital investigations and diagnosis in cases of presenile alzheimers disease. METHOD Reviews of 186 sets of ca...