BACKGROUND Progressive multiple sclerosis is a chronic autoimmune condition of unknown aetiology and few therapeutic options. Human exposure to aluminium has been linked with multiple sclerosis and affected individuals are known to excrete unusually high amounts of aluminium in their urine. Silicon-rich mineral waters facilitate the removal of aluminium from the body in urine and herein we have...

For many years aluminium was not considered harmful to human health because of its relatively low bioavailability. In 1965, however, animal experiments suggested a possible connection between aluminium and Alzheimer’s disease. Oral intake of foodstuffs would appear to be the most important source of aluminium. Consequently, the joint FAO/WHO Expert Committee on Food Additives reduced the provis...

OBJECTIVES The study attempts to define biological indicators of aluminium uptake and excretion in workers exposed to airborne aluminium compounds in a primary aluminium smelter. Also, this study defines the total and respirable aluminium dust fractions in two different potrooms, and correlates their concentrations with biological indicators in this group of workers. METHODS Air was sampled a...

The aetiology of breast cancer is multifactorial. While there are known genetic predispositions to the disease it is probable that environmental factors are also involved. Recent research has demonstrated a regionally specific distribution of aluminium in breast tissue mastectomies while other work has suggested mechanisms whereby breast tissue aluminium might contribute towards the aetiology o...

The features of the formation an intermetallic Ni 3 Al coating by cold spraying a Ni-Al powder mixture mechanically processed in planetary mill and prepared V-shaped mixer are presented. It is shown that deposition efficiency 1.5 times higher when coatings obtained from treated components. Subsequent high-temperature treatment furnace chamber creates condition for compound system various stoich...

Aluminium that has accumulated in the body is thought to have a generalised cytotoxic effect. A prospective study of aluminium accumulation in bone-that is, subclinical aluminium toxicity--was carried out in 94 recipients of kidney allografts, who were followed up for three years. Subclinical aluminium toxicity was found in 66 patients. A significantly smaller proportion of patients with alumin...

BACKGROUND Aluminium toxicity in dialysis patients is well described. Aluminium has a close chemical affinity with silicon. Silicon may have a role in protection against aluminium toxicity. METHODS We measured serum aluminium and silicon levels from haemodialysis patients from four different centres. RESULTS Though no relationship was seen across all centres combined, in one centre there wa...

Aluminium matrix composites (AlMCs) of AA7075 aluminium alloy reinforced with 0.5 and 1 wt.% multiwall carbon nanotubes (MWCNTs) were fabricated powder metallurgy techniques using three different mechanical milling strategies, varying the energy stage in which reinforcements added to pre-alloyed powders. In this paper, we focus on influence these parameters dispersion MWCNTs. Characterization o...

Aluminium is a potent neurotoxin and has been associated with Alzheimer's disease (AD) causality for decades. Prolonged aluminium exposure induces oxidative stress and increases amyloid beta levels in vivo. Current treatment modalities for AD provide only symptomatic relief thus necessitating the development of new drugs with fewer side effects. The aim of the study was to demonstrate the prote...

The demanding material quality criteria in the automotive and aerospace industries have recently had an impact on development of lightweight aluminium alloys. choice application metal-matrix composites as structural materials this context are known to offer a variety benefits. These benefits include ability combine high elastic modulus, toughness, resistance; minimum sensitivity change temperat...