BACKGROUND Fish consumption during infancy has been regarded as a risk factor for allergic disease but later evidence suggests a protective role. However, methodological limitations in the studies make conclusions uncertain. The aim of this study was to assess the association between fish consumption during the first year of life and development of allergic diseases by age 4. METHODS A prospe...

The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies continue to delineate the role of these particles as adjuvants and carriers of al...

OBJECTIVE To describe current ideas about the relation between upper and lower respiratory tract and to review the epidemiological, immunological, and pathological aspects that support the paradigm of united airways disease. SOURCES Literature review using the Medline, MD Consult, HighWire, Medscape and Lilacs databases. We used allergic rhinitis and asthma as keywords, and searched articles ...

Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of the airways. 25-Hydroxyvitamin D [25(OH) Vit D], IL-31, and IL-33 plasma levels were measured in 28 controls (HC), 11 allergic rhinitis (AR) pa...

The apparent rapid increase in IgE-mediated food allergy and its implications are now widely recognized, but little is known about the relationship between family history (an indirect measure of genetic risk) and the risk of food allergy. In a population-based study of 5,276 one year old infants (HealthNuts), the prevalence of oral food challenge-confirmed food allergy was measured. Association...

Since 1983 when patients with type B gastritis were found to be infected by a hitherto unknown type of bacteria showing a certain similarity to Campylobacter, the prognosis of this disease has changed considerably with the availability of highly effective antibiotics. The Gram-negative bacterium was identified as Helicobacter pylori, which causes most cases of gastritis and of peptic and duoden...

OBJECTIVES To investigate the rate of allergic diseases including asthma, allergic rhinitis and eczema in children and adolescents diagnosed with obsessive-compulsive disorder (OCD) (n:26) and/or Tourette syndrome (TS) (n:32) [OCD plus TS, n:13] compared to control subjects (n:35) [total, n:80]. PATIENTS AND METHODS The symptoms of any allergic disease were assessed using the ISAAC questionna...

A new report in the Journal of Clinical Investigation adds to the ever-increasing evidence that immunological mechanisms play an important role in atherogenesis. These new observations suggest involvement of IgE and its Fc R1 receptor in the promotion of atherosclerosis, and specifically in plaque instability and clinical events. Evidence continues to accumulate supporting an important role for...

Allergy in general is a common problem in the community, when all aspects of allergy are considered, this condition may well represent the largest single medical problem seen in the United States today and probably in the world.(1) Allergic rhinitis is the commonest allergic disease. It alone is the sixth most prevalent chronic disease in the world, outranking heart disease. (2) There were six ...

Aim: to assess specific characteristics of exacerbation development in patients with different phenotypes severe asthma (SA) based on the analysis Russian Severe Asthma Registry Respiratory Society. Patients and Methods: this retrospective study assessed risk factors exacerbations, clinical signs, functional laboratory test indicators recorded during disease exacerbations 2060 various SA phenot...