Octyl- and nonylphenols in the environment have been proposed to function as estrogens. To gain insight into their structural essentials in binding to the estrogen receptor, a series of phenols with saturated alkyl groups at the para position, HO-C6H4-CnH2n+1 (n = 0-12), were examined for their ability to displace [3H]17beta-estradiol in the recombinant human estrogen receptor, which was expres...

Abstract Regioselectivity of visible-light-induced transformations a range (hetero)aryl alkyl-substituted ketones bearing several competitive reactive sites ( ? -carbonyl, benzyl and aromatic ring) with N- bromosuccinimide (NBS) was studied under solvent-free reaction conditions (SFRC) in the absence inert-gas atmosphere, radical initiators catalysts. An 8-W energy-saving household lamp used fo...

Atomic-scale chemical modification of surface-adsorbed ethyl groups on Si(001) was induced and studied by means scanning tunneling microscopy. Tunneling at sample bias > +1.5V leads to tip-induced C-H cleavage a $\beta$-hydrogen the covalently bound configuration. The reaction is characterized formation an additional Si-H Si-C bond. probability shows linear dependence current 300 K; largely sup...

A unique palladium-catalyzed arylation of alkyl sulfenate anions is introduced that affords aryl alkyl sulfoxides in high yields. Due to the base sensitivity of the starting sulfoxides, sulfenate anion intermediates, and alkyl aryl sulfoxide products, the use of a mild method to generate alkyl sulfenate anions was crucial to the success of this process. Thus, a fluoride triggered elimination st...

5- hydroxyisoquinoline undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine (15 mol%) to produce the corresponding (E)-alkyl 3-(isoquinolin-5-yloxy) acrylate in good yields. When the reaction was performed by 2-methyl 4-hydroxyquinoline and 3-nitro 4-hydroxypyridine, similar aryl vinyl ethers were obtained.

Molecular dynamics simulations with anion exchange membranes (alkyl trimethyl ammonium grafted onto polysulfone) are performed to investigate the influence of spacer length on transport properties, molecular mechanisms between functional group and aqueous phase hydrogen bond network. This is especially insightful that in this work hydration number small. In condition must be thought as an assem...