The alkali halides interaction with d-ribose in D2O solutions was studied by 1H and 13C NMR spectroscopy. The observed changes in the NMR spectra are interpreted according to a model in which the hydroxyls rich region, from C1 to C4, interacts with the cation while the CH2 group at C5 on the opposite side of the sugar interacts with the anion. It seems, during the salt-sugar interaction, cation...

Alkali (Li(+), Na(+), K(+), Rb(+), and Cs(+)) and halide (F(-), Cl(-), Br(-), and I(-)) ions play an important role in many biological phenomena, roles that range from stabilization of biomolecular structure, to influence on biomolecular dynamics, to key physiological influence on homeostasis and signaling. To properly model ionic interaction and stability in atomistic simulations of biomolecul...