hypertension crisis is one of the main health problems and its effective treatment is of high importance. for this purpose, fast-disintegrating and sustained release formulations of captopril, as a drug of choice, were prepared using conventional mucoadhesive polymers hydroxypropyl methylcellulose (hpmc), sodium carboxymethyl cellulose (na-cmc), hydroxypropyl cellulose (hpc), carbopol 934 (cp93...

RNAi is a gene-silencing phenomenon triggered by double-stranded (ds) RNA and involves the generation of 21 to 26 nt RNA segments that guide mRNA destruction. In Caenorhabditis elegans, lin-4 and let-7 encode small temporal RNAs (stRNAs) of 22 nt that regulate stage-specific development. Here we show that inactivation of genes related to RNAi pathway genes, a homolog of Drosophila Dicer (dcr-1)...

ALG-2, a 22-kDa penta-EF-hand protein, is involved in cell death, signal transduction, membrane trafficking, etc., by interacting with various proteins in mammalian cells in a Ca2+-dependent manner. Most known ALG-2-interacting proteins contain proline-rich regions in which either PPYPXnYP (type 1 motif) or PXPGF (type 2 motif) is commonly found. Previous X-ray crystal structural analysis of th...

Intonational phrasing and pitch accent distribution (PAD) have been proposed to be interdependent (Portuguese) and independent properties of prosodic systems (Egyptian). This paper examines the relation between intonational phrasing and pitch accent distribution in two center-southern varieties of European Portuguese Alentejo (Ale) and Algarve (Alg). Sentences obtained in a reading task systema...

Clinical reactions and serologic in all cases, to alpha globulins in 9 cases, and to SuMM*~y changes after intramuscular adgamma globulins in only 1. This h d i n g indicates ministration of horse anti-human lymphocyte that a safer ALG could be made by removing the globulin (ALG) were studied in 53 human retrace quantities of alpha and beta globulins from cipients of renal homografts. The ALG w...

background and objective: the opportunistic pathogen pseudomonas aeruginosa secrets a capsule-like polysaccharide called alginate which is important for evasion of host defenses, especially in patients with suppressed immunity. method of alginate determination has an important role in the study of microbial alginate. in this study, a novel method for alginate determination by highperformance li...

Then, f ðR ijk;Ri;Rj;RkÞ is either faj; alg; faj; akg or faj; ak; alg: (Only the first two possibilities are mentioned on page 390). In Case A, also consider the possibility that f ðR ijk;Ri;Rj ;RkÞ 1⁄4 faj; ak; alg: Choose RkADE such that falgPkfaj; algPkfajgPkfak; al ; algPkX for any other set X : The proof that k will manipulate at ðR ijk;Ri; % Rj ;RkÞ via Rk is virtually the same as before....

1PM: Oleg Viro (Stony Brook). Multifields (fields with multivalued addition), base fields of tropical geometries. Abstract:In many classical number sets (e.g., complex numbers, real numbers and non-negative real numbers), there are remarkable structures of multifield. Replacing the tropical max-plus semifield in the foundations of tropical geometry by a multifield simplifies the structure of tr...